Fungi and bacteria occupy distinct spatial niches within carious dentin

• Rosalyn M. Sulyanto ,

  Contributed equally to this work with: Rosalyn M. Sulyanto, Clifford J. Beall

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Dentistry, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Department of Developmental Biology, Harvard School of Dental Medicine, Boston, Massachusetts, United States of America

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• Clifford J. Beall ,

  Contributed equally to this work with: Rosalyn M. Sulyanto, Clifford J. Beall

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: beall.3@osu.edu

  Affiliation Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0002-2198-9124

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• Kasey Ha,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliations Department of Dentistry, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Department of Developmental Biology, Harvard School of Dental Medicine, Boston, Massachusetts, United States of America

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• Joseph Montesano ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  ¶‡ JM and JJ also contributed equally to this work.

  Affiliation Harvard School of Dental Medicine, Boston, Massachusetts, United States of America

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• Jason Juang ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  ¶‡ JM and JJ also contributed equally to this work.

  Affiliation Harvard School of Dental Medicine, Boston, Massachusetts, United States of America

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• John R. Dickson,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Shahr B. Hashmi,

  Roles Investigation

  Affiliation Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, United States of America

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• Seth Bradbury,

  Roles Investigation, Resources

  Affiliations Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, United States of America, Division of Pediatric Dentistry, College of Dentistry, The Ohio State University, Columbus, Ohio, United States of America

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• Eugene J. Leys,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision

  Affiliation Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, United States of America

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• Mira Edgerton,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, New York, United States of America

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• Sunita P. Ho,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation Preventive and Restorative Dental Sciences, School of Dentistry, University of California, San Francisco, San Francisco, California, United States of America

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• Ann L. Griffen

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, United States of America, Division of Pediatric Dentistry, College of Dentistry, The Ohio State University, Columbus, Ohio, United States of America

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