Virus specificity and nucleoporin requirements for MX2 activity are affected by GTPase function and capsid-CypA interactions

Bailey Layish; Ram Goli; Haley Flick; Szu-Wei Huang; Robert Z. Zhang; Mamuka Kvaratskhelia; Melissa Kane

doi:10.1371/journal.ppat.1011830

Loading metrics

Open Access

Peer-reviewed

Research Article

Virus specificity and nucleoporin requirements for MX2 activity are affected by GTPase function and capsid-CypA interactions

Bailey Layish,

Roles Investigation

Affiliation Department of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Ram Goli,

Roles Investigation

Affiliation Department of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Haley Flick,

Roles Investigation

Affiliation Department of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Szu-Wei Huang,

Roles Investigation, Methodology

Affiliation Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America
⨯
Robert Z. Zhang,

Roles Investigation, Writing – review & editing

Affiliation Department of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Mamuka Kvaratskhelia,

Roles Methodology, Writing – review & editing

Affiliation Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America
⨯
Melissa Kane

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

* E-mail: kaneme@pitt.edu

Affiliation Department of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

https://orcid.org/0000-0002-4580-1210

⨯

Virus specificity and nucleoporin requirements for MX2 activity are affected by GTPase function and capsid-CypA interactions

Bailey Layish,
Ram Goli,
Haley Flick,
Szu-Wei Huang,
Robert Z. Zhang,
Mamuka Kvaratskhelia,
Melissa Kane

Published: March 21, 2024
https://doi.org/10.1371/journal.ppat.1011830

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

HIV-1
Is the Subject Area "HIV-1" applicable to this article?

Thanks for your feedback.
HT1080 cells
Is the Subject Area "HT1080 cells" applicable to this article?

Thanks for your feedback.
Guanosine triphosphatase
Is the Subject Area "Guanosine triphosphatase" applicable to this article?

Thanks for your feedback.
Viral replication
Is the Subject Area "Viral replication" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Doxycycline
Is the Subject Area "Doxycycline" applicable to this article?

Thanks for your feedback.
HIV-2
Is the Subject Area "HIV-2" applicable to this article?

Thanks for your feedback.
Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.