Mitotic deacetylase complex (MiDAC) recognizes the HIV-1 core promoter to control activated viral gene expression

Emmanuelle Wilhelm; Mikaël Poirier; Morgane Da Rocha; Mikaël Bédard; Patrick P. McDonald; Pierre Lavigne; Christie L. Hunter; Brendan Bell

doi:10.1371/journal.ppat.1011821

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Open Access

Peer-reviewed

Research Article

Mitotic deacetylase complex (MiDAC) recognizes the HIV-1 core promoter to control activated viral gene expression

Emmanuelle Wilhelm,

Roles Data curation, Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation OSE Immunotherapeutics, Nantes, France
⨯
Mikaël Poirier,

Roles Investigation, Methodology, Validation, Writing – review & editing

Affiliation Charles River Laboratories, Sherbrooke, Québec, Canada
⨯
Morgane Da Rocha,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Département de microbiologie et d’infectiologie, Faculté de médecine et sciences de la santé, Université de Sherbrooke, and Centre de recherche du CHUS, Sherbrooke, Québec, Canada
⨯
Mikaël Bédard,

Roles Investigation

Affiliation Département de Biochimie et de Génomique Fonctionnelle, Faculté de médecine et sciences de la santé, Université de Sherbrooke, and Centre de recherche du CHUS, Sherbrooke, Québec, Canada
⨯
Patrick P. McDonald,

Roles Investigation, Methodology

Affiliation Pulmonary Division, Medicine Faculty, Université de Sherbrooke; and Centre de recherche du CHUS, Sherbrooke, Québec, Canada
⨯
Pierre Lavigne,

Roles Conceptualization, Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing

Affiliation Département de Biochimie et de Génomique Fonctionnelle, Faculté de médecine et sciences de la santé, Université de Sherbrooke, and Centre de recherche du CHUS, Sherbrooke, Québec, Canada
⨯
Christie L. Hunter,

Roles Conceptualization, Data curation, Investigation, Methodology, Writing – review & editing

Affiliation SCIEX, Redwood City, California, United States of America
⨯
Brendan Bell

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: Brendan.Bell@USherbrooke.ca

Affiliation Département de microbiologie et d’infectiologie, Faculté de médecine et sciences de la santé, Université de Sherbrooke, and Centre de recherche du CHUS, Sherbrooke, Québec, Canada

https://orcid.org/0000-0001-6885-940X

⨯

Mitotic deacetylase complex (MiDAC) recognizes the HIV-1 core promoter to control activated viral gene expression

Emmanuelle Wilhelm,
Mikaël Poirier,
Morgane Da Rocha,
Mikaël Bédard,
Patrick P. McDonald,
Pierre Lavigne,
Christie L. Hunter,
Brendan Bell

Published: May 23, 2024
https://doi.org/10.1371/journal.ppat.1011821

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