Plasmodium falciparum utilizes pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stage

Omobukola Solebo; Liqin Ling; Ikechukwu Nwankwo; Jing Zhou; Tian-Min Fu; Hangjun Ke

doi:10.1371/journal.ppat.1011818

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Peer-reviewed

Research Article

Plasmodium falciparum utilizes pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stage

Omobukola Solebo,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Center for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Liqin Ling,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliations Center for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China
⨯
Ikechukwu Nwankwo,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Center for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Jing Zhou,

Roles Supervision, Writing – review & editing

Affiliation Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China
⨯
Tian-Min Fu,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliations Department of Biological Chemistry and Pharmacology, The Ohio State University College of Medicine, Columbus, Ohio, United States of America, The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America
⨯
Hangjun Ke

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: hk84@drexel.edu

Affiliation Center for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

https://orcid.org/0000-0002-2006-3987

⨯

Plasmodium falciparum utilizes pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stage

Omobukola Solebo,
Liqin Ling,
Ikechukwu Nwankwo,
Jing Zhou,
Tian-Min Fu,
Hangjun Ke

Published: December 4, 2023
https://doi.org/10.1371/journal.ppat.1011818

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