Brain tropism acquisition: The spatial dynamics and evolution of a measles virus collective infectious unit that drove lethal subacute sclerosing panencephalitis

• Iris Yousaf ,

  Contributed equally to this work with: Iris Yousaf, William W. Hannon

  Roles Conceptualization, Data curation, Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, Minnesota, United States of America

  ⨯
• William W. Hannon ,

  Contributed equally to this work with: Iris Yousaf, William W. Hannon

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization

  Affiliations Basic Sciences and Computational Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America, Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America

  ⨯
• Ryan C. Donohue,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Mayo Clinic Graduate School of Biomedical Sciences, Rochester, Minnesota, United States of America

  ⨯
• Christian K. Pfaller,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, Minnesota, United States of America

  ⨯
• Kalpana Yadav,

  Roles Resources, Writing – review & editing

  Affiliation Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Ryan J. Dikdan,

  Roles Formal analysis, Writing – review & editing

  Affiliation Public Health Research Institute, Rutgers University, Newark, New Jersey, United States of America

  ⨯
• Sanjay Tyagi,

  Roles Conceptualization, Data curation, Supervision, Writing – review & editing

  Affiliation Public Health Research Institute, Rutgers University, Newark, New Jersey, United States of America

  ⨯
• Declan C. Schroeder,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Veterinary Population Medicine, University of Minnesota, St Paul, Minnesota, United States of America

  ⨯
• Wun-Ju Shieh,

  Roles Formal analysis, Writing – review & editing

  Current address: Department of Microbiology and Immunology, Taipei Medical University, Taipei, Taiwan

  Affiliation Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, Center for Disease Control and Prevention, Atlanta, Georgia, United States of America

  ⨯
• Paul A. Rota,

  Roles Conceptualization, Investigation, Resources, Writing – review & editing

  Affiliation Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Center for Disease Control and Prevention, Atlanta, Georgia, United States of America

  ⨯
• Alison F. Feder ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Supervision, Visualization, Writing – original draft

  * E-mail: affeder@uw.edu (AFF); Cattaneo.Roberto@mayo.edu (RC)

  Affiliations Genome Sciences, University of Washington, Seattle, Washington, United States of America, Public Health Sciences and Computational Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

  ⨯
• Roberto Cattaneo

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft

  * E-mail: affeder@uw.edu (AFF); Cattaneo.Roberto@mayo.edu (RC)

  Affiliations Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, Minnesota, United States of America

  https://orcid.org/0000-0001-6881-2548

  ⨯