SARS-CoV-2 suppresses TLR4-induced immunity by dendritic cells via C-type lectin receptor DC-SIGN

Lieve E. H. van der Donk; Marta Bermejo-Jambrina; John L. van Hamme; Mette M. W. Volkers; Ad C. van Nuenen; Neeltje A. Kootstra; Teunis B. H. Geijtenbeek

doi:10.1371/journal.ppat.1011735

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Open Access

Peer-reviewed

Research Article

SARS-CoV-2 suppresses TLR4-induced immunity by dendritic cells via C-type lectin receptor DC-SIGN

Lieve E. H. van der Donk,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands, Amsterdam institute for Infection and Immunity, Infectious Diseases, Amsterdam, The Netherlands
⨯
Marta Bermejo-Jambrina,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

Affiliations Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands, Amsterdam institute for Infection and Immunity, Infectious Diseases, Amsterdam, The Netherlands, Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria
⨯
John L. van Hamme,

Roles Data curation, Investigation, Methodology

Affiliations Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands, Amsterdam institute for Infection and Immunity, Infectious Diseases, Amsterdam, The Netherlands
⨯
Mette M. W. Volkers,

Roles Data curation, Investigation, Methodology

Affiliations Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands, Amsterdam institute for Infection and Immunity, Infectious Diseases, Amsterdam, The Netherlands
⨯
Ad C. van Nuenen,

Roles Data curation, Investigation, Methodology, Resources

Affiliations Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands, Amsterdam institute for Infection and Immunity, Infectious Diseases, Amsterdam, The Netherlands
⨯
Neeltje A. Kootstra,

Roles Investigation, Methodology, Resources, Writing – review & editing

Affiliations Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands, Amsterdam institute for Infection and Immunity, Infectious Diseases, Amsterdam, The Netherlands
⨯
Teunis B. H. Geijtenbeek

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Visualization, Writing – review & editing

* E-mail: t.b.geijtenbeek@amsterdamumc.nl

Affiliations Department of Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands, Amsterdam institute for Infection and Immunity, Infectious Diseases, Amsterdam, The Netherlands

https://orcid.org/0000-0002-5710-2839

⨯

SARS-CoV-2 suppresses TLR4-induced immunity by dendritic cells via C-type lectin receptor DC-SIGN

Lieve E. H. van der Donk,
Marta Bermejo-Jambrina,
John L. van Hamme,
Mette M. W. Volkers,
Ad C. van Nuenen,
Neeltje A. Kootstra,
Teunis B. H. Geijtenbeek

Published: October 16, 2023
https://doi.org/10.1371/journal.ppat.1011735

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