G9a and Sirtuin6 epigenetically modulate host cholesterol accumulation to facilitate mycobacterial survival

Praveen Prakhar; Bharat Bhatt; Gaurav Kumar Lohia; Awantika Shah; Tanushree Mukherjee; Ullas Kolthur-Seetharam; Nagalingam R. Sundaresan; Raju S. Rajmani; Kithiganahalli Narayanaswamy Balaji

doi:10.1371/journal.ppat.1011731

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Open Access

Peer-reviewed

Research Article

G9a and Sirtuin6 epigenetically modulate host cholesterol accumulation to facilitate mycobacterial survival

Praveen Prakhar ,

Contributed equally to this work with: Praveen Prakhar, Bharat Bhatt, Gaurav Kumar Lohia, Awantika Shah, Tanushree Mukherjee

Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, Karnataka, India
⨯
Bharat Bhatt ,

Contributed equally to this work with: Praveen Prakhar, Bharat Bhatt, Gaurav Kumar Lohia, Awantika Shah, Tanushree Mukherjee

Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, Karnataka, India
⨯
Gaurav Kumar Lohia ,

Contributed equally to this work with: Praveen Prakhar, Bharat Bhatt, Gaurav Kumar Lohia, Awantika Shah, Tanushree Mukherjee

Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, Karnataka, India
⨯
Awantika Shah ,

Contributed equally to this work with: Praveen Prakhar, Bharat Bhatt, Gaurav Kumar Lohia, Awantika Shah, Tanushree Mukherjee

Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, Karnataka, India
⨯
Tanushree Mukherjee ,

Contributed equally to this work with: Praveen Prakhar, Bharat Bhatt, Gaurav Kumar Lohia, Awantika Shah, Tanushree Mukherjee

Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, Karnataka, India
⨯
Ullas Kolthur-Seetharam,

Roles Resources

Affiliation Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, Maharashtra, India
⨯
Nagalingam R. Sundaresan,

Roles Resources

Affiliation Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, Karnataka, India
⨯
Raju S. Rajmani,

Roles Investigation

Affiliation Centre for Infectious Disease Research, Indian Institute of Science, Bangalore–, Karnataka, India
⨯
Kithiganahalli Narayanaswamy Balaji

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: balaji@iisc.ac.in

Affiliation Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, Karnataka, India

https://orcid.org/0000-0002-0006-5707

⨯

G9a and Sirtuin6 epigenetically modulate host cholesterol accumulation to facilitate mycobacterial survival

Praveen Prakhar,
Bharat Bhatt,
Gaurav Kumar Lohia,
Awantika Shah,
Tanushree Mukherjee,
Ullas Kolthur-Seetharam,
Nagalingam R. Sundaresan,
Raju S. Rajmani,
Kithiganahalli Narayanaswamy Balaji

Published: October 23, 2023
https://doi.org/10.1371/journal.ppat.1011731

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