Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody

• Tin Phan,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Theoretical Biology & Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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• Carolin Zitzmann,

  Roles Investigation, Software, Writing – original draft, Writing – review & editing

  Affiliation Theoretical Biology & Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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• Kara W. Chew,

  Roles Data curation, Investigation, Resources, Writing – review & editing

  Affiliation Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, United States of America

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• Davey M. Smith,

  Roles Data curation, Investigation, Resources

  Affiliation Department of Medicine, University of California, San Diego, California, United States of America

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• Eric S. Daar,

  Roles Data curation, Resources

  Affiliation Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America

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• David A. Wohl,

  Roles Data curation, Resources

  Affiliation Department of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America

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• Joseph J. Eron,

  Roles Data curation, Resources

  Affiliation Department of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America

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• Judith S. Currier,

  Roles Data curation, Investigation, Resources

  Affiliation Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, United States of America

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• Michael D. Hughes,

  Roles Data curation, Investigation, Resources

  Affiliation Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America

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• Manish C. Choudhary,

  Roles Data curation, Investigation, Resources

  Affiliation Department of Medicine, Division of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Rinki Deo,

  Roles Data curation, Investigation, Resources

  Affiliation Department of Medicine, Division of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Jonathan Z. Li,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Department of Medicine, Division of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Ruy M. Ribeiro,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Theoretical Biology & Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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• Ruian Ke,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Theoretical Biology & Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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• Alan S. Perelson ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: asp@lanl.gov

  Affiliations Theoretical Biology & Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America, Santa Fe Institute, Santa Fe, New Mexico, United States of America

  https://orcid.org/0000-0002-2455-0002

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