Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core

Mélissa Bessonne; Jessica Morel; Quentin Nevers; Bruno Da Costa; Allison Ballandras-Colas; Florian Chenavier; Magali Grange; Alain Roussel; Thibaut Crépin; Bernard Delmas

doi:10.1371/journal.ppat.1011642

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Open Access

Peer-reviewed

Research Article

Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core

Mélissa Bessonne ,

Contributed equally to this work with: Mélissa Bessonne, Jessica Morel

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

Affiliation Unité de Virologie et Immunologie moléculaires, INRAE, Université Paris-Saclay, Jouy-en-Josas, France
⨯
Jessica Morel ,

Contributed equally to this work with: Mélissa Bessonne, Jessica Morel

Roles Formal analysis, Investigation, Methodology

Affiliation Unité de Virologie et Immunologie moléculaires, INRAE, Université Paris-Saclay, Jouy-en-Josas, France
⨯
Quentin Nevers,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Unité de Virologie et Immunologie moléculaires, INRAE, Université Paris-Saclay, Jouy-en-Josas, France
⨯
Bruno Da Costa,

Roles Investigation

Affiliation Unité de Virologie et Immunologie moléculaires, INRAE, Université Paris-Saclay, Jouy-en-Josas, France
⨯
Allison Ballandras-Colas,

Roles Investigation, Methodology

Affiliation Institut de biologie structurale, CNRS, Université de Grenoble, Grenoble, France
⨯
Florian Chenavier,

Roles Visualization

Affiliation Institut de biologie structurale, CNRS, Université de Grenoble, Grenoble, France
⨯
Magali Grange,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Laboratoire d’Ingénierie des Systèmes Macromoléculaires (LISM), CNRS, Université d’Aix-Marseille, Marseille, France
⨯
Alain Roussel,

Roles Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – review & editing

Affiliation Laboratoire d’Ingénierie des Systèmes Macromoléculaires (LISM), CNRS, Université d’Aix-Marseille, Marseille, France
⨯
Thibaut Crépin,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Institut de biologie structurale, CNRS, Université de Grenoble, Grenoble, France
⨯
Bernard Delmas

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Resources, Writing – original draft, Writing – review & editing

* E-mail: bernard.delmas@inrae.fr

Affiliation Unité de Virologie et Immunologie moléculaires, INRAE, Université Paris-Saclay, Jouy-en-Josas, France

https://orcid.org/0000-0002-2713-4768

⨯

Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core

Mélissa Bessonne,
Jessica Morel,
Quentin Nevers,
Bruno Da Costa,
Allison Ballandras-Colas,
Florian Chenavier,
Magali Grange,
Alain Roussel,
Thibaut Crépin,
Bernard Delmas

Published: June 14, 2024
https://doi.org/10.1371/journal.ppat.1011642

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Influenza viruses
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