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Open Access
Peer-reviewed
Research Article
Influenza A virus inhibits TET2 expression by endoribonuclease PA-X to attenuate type I interferon signaling and promote viral replication
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Yixiang Hu,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft
Affiliations Department of Veterinary Medicine & Institute of Preventive Veterinary Sciences, Zhejiang University College of Animal Sciences, Hangzhou, Zhejiang, China, Hainan Institute of Zhejiang University, Sanya, Hainan, China, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, Hangzhou, Zhejiang, China
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Xinru Chen,
Roles Investigation, Methodology
Affiliations Department of Veterinary Medicine & Institute of Preventive Veterinary Sciences, Zhejiang University College of Animal Sciences, Hangzhou, Zhejiang, China, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, Hangzhou, Zhejiang, China
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Yuehuan Ling,
Roles Investigation, Methodology
Affiliations Department of Veterinary Medicine & Institute of Preventive Veterinary Sciences, Zhejiang University College of Animal Sciences, Hangzhou, Zhejiang, China, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, Hangzhou, Zhejiang, China
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Kun Zhou,
Roles Investigation, Methodology
Affiliations Department of Veterinary Medicine & Institute of Preventive Veterinary Sciences, Zhejiang University College of Animal Sciences, Hangzhou, Zhejiang, China, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, Hangzhou, Zhejiang, China
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Meiqing Han,
Roles Investigation
Affiliations Department of Veterinary Medicine & Institute of Preventive Veterinary Sciences, Zhejiang University College of Animal Sciences, Hangzhou, Zhejiang, China, Hainan Institute of Zhejiang University, Sanya, Hainan, China, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, Hangzhou, Zhejiang, China
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Xingbo Wang,
Roles Methodology
Affiliation Department of Veterinary Medicine & Institute of Preventive Veterinary Sciences, Zhejiang University College of Animal Sciences, Hangzhou, Zhejiang, China
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Min Yue,
Roles Methodology
Affiliations Department of Veterinary Medicine & Institute of Preventive Veterinary Sciences, Zhejiang University College of Animal Sciences, Hangzhou, Zhejiang, China, Hainan Institute of Zhejiang University, Sanya, Hainan, China, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, Hangzhou, Zhejiang, China, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
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Yan Li
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: yanli3@zju.edu.cn
Affiliations Department of Veterinary Medicine & Institute of Preventive Veterinary Sciences, Zhejiang University College of Animal Sciences, Hangzhou, Zhejiang, China, Hainan Institute of Zhejiang University, Sanya, Hainan, China, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, Hangzhou, Zhejiang, China
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Influenza A virus inhibits TET2 expression by endoribonuclease PA-X to attenuate type I interferon signaling and promote viral replication
- Yixiang Hu,
- Xinru Chen,
- Yuehuan Ling,
- Kun Zhou,
- Meiqing Han,
- Xingbo Wang,
- Min Yue,
- Yan Li
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- Published: July 27, 2023
- https://doi.org/10.1371/journal.ppat.1011550