Pathogenesis and outcome of VA1 astrovirus infection in the human brain are defined by disruption of neural functions and imbalanced host immune responses

• Olga A. Maximova ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: maximovao@niaid.nih.gov (OAM); jcohen@niaid.nih.gov (JIC)

  Affiliation Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-8906-9738

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• Melodie L. Weller,

  Roles Data curation, Formal analysis, Methodology

  Current address: University of Utah, Salt Lake City, Utah, United States of America

  Affiliation Secretory Physiology Section, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America

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• Tammy Krogmann,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Daniel E. Sturdevant,

  Roles Data curation, Formal analysis, Methodology, Software, Validation

  Affiliation Research Technologies Branch, Genomics Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America

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• Stacy Ricklefs,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Research Technologies Branch, Genomics Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America

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• Kimmo Virtaneva,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Research Technologies Branch, Genomics Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America

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• Craig Martens,

  Roles Methodology, Project administration, Supervision

  Affiliation Research Technologies Branch, Genomics Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America

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• Kurt Wollenberg,

  Roles Data curation, Formal analysis, Methodology, Software, Visualization

  Affiliation Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Mahnaz Minai,

  Roles Formal analysis, Methodology

  Affiliation Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Ian N. Moore,

  Roles Methodology, Supervision

  Current address: Emory National Primate Research Center, Emory University, Atlanta, Georgia, United States of America

  Affiliation Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Craig S. Sauter,

  Roles Data curation, Investigation, Resources

  Affiliation Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Juliet N. Barker,

  Roles Investigation, Resources

  Affiliation Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• W. Ian Lipkin,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America

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• Danielle Seilhean,

  Roles Investigation, Resources

  Affiliation Sorbonne Université, Paris, France

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• Avindra Nath,

  Roles Conceptualization

  Affiliation Infections of the Nervous System Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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•  [ ... ],
• Jeffrey I. Cohen

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: maximovao@niaid.nih.gov (OAM); jcohen@niaid.nih.gov (JIC)

  Affiliation Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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