Suppression of viral RNA polymerase activity is necessary for persistent infection during the transformation of measles virus into SSPE virus

Kento Sakamoto; Miho Konami; Shinra Kameda; Yuto Satoh; Hiroshi Wakimoto; Yoshinori Kitagawa; Bin Gotoh; Da-Peng Jiang; Hak Hotta; Masae Itoh

doi:10.1371/journal.ppat.1011528

Loading metrics

Open Access

Peer-reviewed

Research Article

Suppression of viral RNA polymerase activity is necessary for persistent infection during the transformation of measles virus into SSPE virus

Kento Sakamoto,

Roles Formal analysis, Investigation, Methodology, Project administration, Writing – original draft

Affiliation Department of Microbiology, Faculty of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan
⨯
Miho Konami,

Roles Investigation

Affiliation Department of Microbiology, Faculty of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan
⨯
Shinra Kameda,

Roles Investigation

Affiliation Department of Microbiology, Faculty of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan
⨯
Yuto Satoh,

Roles Funding acquisition, Methodology, Project administration, Visualization

Affiliation Department of Microbiology, Faculty of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan
⨯
Hiroshi Wakimoto,

Roles Investigation, Methodology, Visualization

Affiliation Department of Microbiology, Faculty of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan
⨯
Yoshinori Kitagawa,

Roles Data curation, Validation

Affiliation Division of Microbiology and Infectious Diseases, Department of Pathology, Shiga University of Medical Science, Otsu, Shiga, Japan
⨯
Bin Gotoh,

Roles Data curation, Validation

Affiliation Division of Microbiology and Infectious Diseases, Department of Pathology, Shiga University of Medical Science, Otsu, Shiga, Japan
⨯
Da-Peng Jiang,

Roles Investigation

Affiliation Graduate School of Medicine, Kobe University, Kobe, Hyogo, Japan
⨯
Hak Hotta,

Roles Conceptualization, Supervision

Affiliation Graduate School of Medicine, Kobe University, Kobe, Hyogo, Japan
⨯
Masae Itoh

Roles Conceptualization, Formal analysis, Funding acquisition, Resources, Supervision, Writing – original draft

* E-mail: m_itoh@nagahama-i-bio.ac.jp

Affiliation Department of Microbiology, Faculty of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan
⨯

Suppression of viral RNA polymerase activity is necessary for persistent infection during the transformation of measles virus into SSPE virus

Kento Sakamoto,
Miho Konami,
Shinra Kameda,
Yuto Satoh,
Hiroshi Wakimoto,
Yoshinori Kitagawa,
Bin Gotoh,
Da-Peng Jiang,
Hak Hotta,
Masae Itoh

Published: July 26, 2023
https://doi.org/10.1371/journal.ppat.1011528

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Measles virus
Is the Subject Area "Measles virus" applicable to this article?

Thanks for your feedback.
Cell fusion
Is the Subject Area "Cell fusion" applicable to this article?

Thanks for your feedback.
Microbial mutation
Is the Subject Area "Microbial mutation" applicable to this article?

Thanks for your feedback.
Viral persistence and latency
Is the Subject Area "Viral persistence and latency" applicable to this article?

Thanks for your feedback.
Neuropathy
Is the Subject Area "Neuropathy" applicable to this article?

Thanks for your feedback.
Viral genomics
Is the Subject Area "Viral genomics" applicable to this article?

Thanks for your feedback.
Fluorescence microscopy
Is the Subject Area "Fluorescence microscopy" applicable to this article?

Thanks for your feedback.
Point mutation
Is the Subject Area "Point mutation" applicable to this article?

Thanks for your feedback.