-
Loading metrics
Open Access
Peer-reviewed
Research Article
NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner
-
Fakhar H. Waqas,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing
Affiliations Research Group Biomarkers for Infectious Diseases, TWINCORE Centre for Experimental and Clinical Infection Research, Hannover, Germany, Research Group Biomarkers for Infectious Diseases, Helmholtz Centre for Infection Research, Braunschweig, Germany
⨯ -
Mahmoud Shehata ,
Contributed equally to this work with: Mahmoud Shehata, Walid A. M. Elgaher, Antoine Lacour
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliations Institute of Medical Virology, Justus-Liebig-University Giessen, Giessen, Germany, National Research Centre, Giza, Egypt
⨯ -
Walid A. M. Elgaher ,
Contributed equally to this work with: Mahmoud Shehata, Walid A. M. Elgaher, Antoine Lacour
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing
Affiliation Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) – Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany
⨯ -
Antoine Lacour ,
Contributed equally to this work with: Mahmoud Shehata, Walid A. M. Elgaher, Antoine Lacour
Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliations Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) – Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany, Institute for Experimental Infection Research, TWINCORE Centre for Experimental and Clinical Infection Research, Hannover, Germany
⨯ -
Naziia Kurmasheva,
Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Biomedicine, Aarhus University, Aarhus, Denmark
⨯ -
Fabio Begnini,
Roles Investigation, Methodology
Affiliation Department of Chemistry, Aarhus University, Aarhus, Denmark
⨯ -
Anders E. Kiib,
Roles Investigation, Methodology
Affiliation Department of Chemistry, Aarhus University, Aarhus, Denmark
⨯ -
Julia Dahlmann,
Roles Investigation, Methodology
Affiliations Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiothoracic, Transplantation and Vascular Surgery (HTTG), REBIRTH-Research Center for Translational and Regenerative Medicine, Hannover Medical School, Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany
⨯ -
Chutao Chen,
Roles Investigation, Project administration
Affiliations Research Group Biomarkers for Infectious Diseases, TWINCORE Centre for Experimental and Clinical Infection Research, Hannover, Germany, Research Group Biomarkers for Infectious Diseases, Helmholtz Centre for Infection Research, Braunschweig, Germany
⨯ -
Andreas Pavlou,
Roles Formal analysis, Resources, Supervision, Visualization
Affiliation Institute for Experimental Infection Research, TWINCORE Centre for Experimental and Clinical Infection Research, Hannover, Germany
⨯ -
Thomas B. Poulsen,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing
Affiliation Department of Chemistry, Aarhus University, Aarhus, Denmark
⨯ -
Sylvia Merkert,
Roles Investigation, Methodology, Resources
Affiliations Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiothoracic, Transplantation and Vascular Surgery (HTTG), REBIRTH-Research Center for Translational and Regenerative Medicine, Hannover Medical School, Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany
⨯ -
Ulrich Martin,
Roles Conceptualization, Funding acquisition, Resources, Supervision
Affiliations Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiothoracic, Transplantation and Vascular Surgery (HTTG), REBIRTH-Research Center for Translational and Regenerative Medicine, Hannover Medical School, Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany
⨯ -
Ruth Olmer,
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – review & editing
Affiliations Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiothoracic, Transplantation and Vascular Surgery (HTTG), REBIRTH-Research Center for Translational and Regenerative Medicine, Hannover Medical School, Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany
⨯ -
David Olagnier,
Roles Conceptualization, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing
Affiliation Department of Biomedicine, Aarhus University, Aarhus, Denmark
⨯ -
Anna K. H. Hirsch,
Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing
Affiliations Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) – Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany, Department of Pharmacy, Saarland University, Saarbrücken, Germany
⨯ -
Stephan Pleschka,
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing
Affiliations Institute of Medical Virology, Justus-Liebig-University Giessen, Giessen, Germany, German Center for Infection Research, partner site Giessen, Germany
⨯ - [ ... ],
-
Frank Pessler
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: frank.pessler@helmholtz-hzi.de
Affiliations Research Group Biomarkers for Infectious Diseases, TWINCORE Centre for Experimental and Clinical Infection Research, Hannover, Germany, Research Group Biomarkers for Infectious Diseases, Helmholtz Centre for Infection Research, Braunschweig, Germany, Centre for Individualised Infection Medicine, Hannover, Germany
⨯ - [ view all ]
- [ view less ]
NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner
- Fakhar H. Waqas,
- Mahmoud Shehata,
- Walid A. M. Elgaher,
- Antoine Lacour,
- Naziia Kurmasheva,
- Fabio Begnini,
- Anders E. Kiib,
- Julia Dahlmann,
- Chutao Chen,
- Andreas Pavlou
-
- Published: July 17, 2023
- https://doi.org/10.1371/journal.ppat.1011506
- See the preprint