The synergistic effect of residues 32T and 550L in the PA protein of H5 subtype avian influenza virus contributes to viral pathogenicity in mice

• Hui Yang ,

  Contributed equally to this work with: Hui Yang, Yurui Dong

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China

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• Yurui Dong ,

  Contributed equally to this work with: Hui Yang, Yurui Dong

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China

  ⨯
• Ying Bian,

  Roles Methodology

  Affiliation College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China

  ⨯
• Chenzhi Huo,

  Roles Methodology

  Affiliation College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China

  ⨯
• Chuncheng Zhu,

  Roles Methodology

  Affiliation College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China

  ⨯
• Tao Qin,

  Roles Data curation, Funding acquisition

  Affiliations College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China, Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou, Jiangsu, China, Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China, Jiangsu Research Centre of Engineering and Technology for Prevention and Control of Poultry Disease, Yangzhou, Jiangsu, China

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• Sujuan Chen ,

  Roles Data curation, Funding acquisition, Resources

  * E-mail: chensj@yzu.edu.cn (SC); pengdx@yzu.edu.cn (DP)

  Affiliations College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China, Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou, Jiangsu, China, Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China, Jiangsu Research Centre of Engineering and Technology for Prevention and Control of Poultry Disease, Yangzhou, Jiangsu, China

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• Daxin Peng ,

  Roles Conceptualization, Data curation, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: chensj@yzu.edu.cn (SC); pengdx@yzu.edu.cn (DP)

  Affiliations College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China, Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou, Jiangsu, China, Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China, Jiangsu Research Centre of Engineering and Technology for Prevention and Control of Poultry Disease, Yangzhou, Jiangsu, China

  https://orcid.org/0000-0001-6773-5149

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• Xiufan Liu

  Roles Resources

  Affiliations College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China, Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou, Jiangsu, China, Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China, Jiangsu Research Centre of Engineering and Technology for Prevention and Control of Poultry Disease, Yangzhou, Jiangsu, China

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