Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection

• Patricia Aguilar-Calvo ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft

  * E-mail: paguilarcalvo@uabmc.edu (PA-C); csigurdson@health.ucsd.edu (CJS)

  Current address: Department of Neurology, University of Alabama, Birmingham, Alabama, United States of America

  Affiliation Department of Pathology, UC San Diego, La Jolla, California, United States of America

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• Adela Malik,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Current address: Bristol Myers Squibb, San Diego, California, United States of America

  Affiliation Department of Pathology, UC San Diego, La Jolla, California, United States of America

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• Daniel R. Sandoval,

  Roles Conceptualization, Data curation, Investigation, Methodology

  Current address: Pfizer, San Diego, California, United States of America

  Affiliation Department of Cellular and Molecular Medicine, UC San Diego, La Jolla, California, United States of America

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• Christopher Barback,

  Roles Data curation, Investigation, Methodology

  Current address: Fate Therapeutics, San Diego, California, United States of America

  Affiliation Department of Radiology, UC San Diego, La Jolla, California, United States of America

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• Christina D. Orrù,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, United States of America

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• Heidi G. Standke,

  Roles Data curation, Investigation

  Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Olivia R. Thomas,

  Roles Data curation, Investigation

  Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Chrissa A. Dwyer,

  Roles Conceptualization, Investigation

  Current address: GSK plc, Collegeville, Philadelphia, United States of America

  Affiliation Department of Cellular and Molecular Medicine, UC San Diego, La Jolla, California, United States of America

  ⨯
• Donald P. Pizzo,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Pathology, UC San Diego, La Jolla, California, United States of America

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• Jaidev Bapat,

  Roles Data curation, Investigation

  Current address: Department of Obstetrics & Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America

  Affiliation Department of Pathology, UC San Diego, La Jolla, California, United States of America

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• Katrin Soldau,

  Roles Data curation, Investigation

  Affiliation Department of Pathology, UC San Diego, La Jolla, California, United States of America

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• Ryotaro Ogawa,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Radiology, UC San Diego, La Jolla, California, United States of America

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• Mckenzie B. Riley,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Neurology, University of Alabama, Birmingham, Alabama, United States of America

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• K. Peter R. Nilsson,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Physics, Chemistry, and Biology, Linköping University, Linköping, Sweden

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• Allison Kraus,

  Roles Formal analysis, Investigation, Supervision, Validation, Writing – review & editing

  Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Byron Caughey,

  Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, United States of America

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• Jeffrey J. Iliff,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliations VISN 20 NW Mental Illness Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington, United States of America, Department of Psychiatry and Behavioral Science, Department of Neurology, University of Washington School of Medicine, Seattle, Washington, United States of America

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• David R. Vera,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Radiology, UC San Diego, La Jolla, California, United States of America

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• Jeffrey D. Esko,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Department of Cellular and Molecular Medicine, UC San Diego, La Jolla, California, United States of America

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•  [ ... ],
• Christina J. Sigurdson

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft

  * E-mail: paguilarcalvo@uabmc.edu (PA-C); csigurdson@health.ucsd.edu (CJS)

  Affiliations Department of Pathology, UC San Diego, La Jolla, California, United States of America, Department of Medicine, UC San Diego, La Jolla, California, United States of America, Department of Pathology, Microbiology, and Immunology, UC Davis, Davis, California, United States of America

  https://orcid.org/0000-0002-1770-0965

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