Neutralization profiles of HIV-1 viruses from the VRC01 Antibody Mediated Prevention (AMP) trials

• Nonhlanhla N. Mkhize ,

  Roles Conceptualization, Formal analysis, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: nonom@nicd.ac.za

  Affiliations National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa, SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

  https://orcid.org/0000-0003-3037-1243

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• Anna E. J. Yssel,

  Roles Data curation, Formal analysis, Visualization, Writing – review & editing

  Affiliation Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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• Haajira Kaldine,

  Roles Investigation

  Affiliations National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa, SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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• Rebecca T. van Dorsten,

  Roles Formal analysis, Investigation, Visualization

  Affiliations National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa, SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, South African Medical Research Council Antiviral Gene Therapy Research Unit, School of Pathology, Faculty of Health Sciences University of the Witwatersrand, Johannesburg, South Africa

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• Amanda S. Woodward Davis,

  Roles Visualization, Writing – original draft, Writing – review & editing

  Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

  https://orcid.org/0000-0002-6901-8271

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• Nicolas Beaume,

  Roles Data curation, Formal analysis, Visualization

  Affiliation Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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• David Matten,

  Roles Data curation, Formal analysis, Visualization

  Affiliation Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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• Bronwen Lambson,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliations National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa, SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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• Tandile Modise,

  Roles Investigation

  Affiliations National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa, SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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• Prudence Kgagudi,

  Roles Investigation

  Affiliations National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa, SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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• Talita York,

  Roles Project administration

  Affiliation Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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• Dylan H. Westfall,

  Roles Data curation, Formal analysis

  Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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• Elena E. Giorgi,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

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• Bette Korber,

  Roles Formal analysis, Methodology

  Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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• Colin Anthony,

  Roles Formal analysis, Investigation

  Affiliation Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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• Rutendo E. Mapengo,

  Roles Investigation

  Affiliations National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa, SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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• Valerie Bekker,

  Roles Investigation

  Affiliation National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa

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• Elizabeth Domin,

  Roles Investigation

  Affiliation Department of Surgery, Duke University, Durham, North Carolina, United States of America

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• Amanda Eaton,

  Roles Project administration

  Affiliation Department of Surgery, Duke University, Durham, North Carolina, United States of America

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• Wenjie Deng,

  Roles Formal analysis

  Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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• Allan DeCamp,

  Roles Conceptualization, Methodology

  Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

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• Yunda Huang,

  Roles Methodology, Writing – review & editing

  Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

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• Peter B. Gilbert,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

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• Asanda Gwashu-Nyangiwe,

  Roles Investigation

  Affiliation Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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• Ruwayhida Thebus,

  Roles Investigation

  Affiliation Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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• Nonkululeko Ndabambi,

  Roles Investigation

  Affiliation Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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• Dieter Mielke,

  Roles Investigation

  Affiliations Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa, Department of Surgery, Duke University, Durham, North Carolina, United States of America

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• Nyaradzo Mgodi,

  Roles Supervision

  Affiliation University of Zimbabwe College of Health Sciences Clinical Trials Research Centre, Harare, Zimbabwe

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• Shelly Karuna,

  Roles Supervision, Writing – review & editing

  Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

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• Srilatha Edupuganti,

  Roles Supervision

  Affiliation Division of Infectious Diseases, Department of Medicine, Emory University, Decatur, Georgia, United States of America

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• Michael S. Seaman,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

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• Lawrence Corey,

  Roles Conceptualization, Funding acquisition, Resources

  Affiliations Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America, Department of Laboratory Medicine, University of Washington, Seattle, Washington, United States of America

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• Myron S. Cohen,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North-Carolina, United States of America

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• John Hural,

  Roles Project administration

  Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

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• M. Juliana McElrath,

  Roles Funding acquisition

  Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

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• James I. Mullins,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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• David Montefiori,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Surgery, Duke University, Durham, North Carolina, United States of America

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• Penny L. Moore,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliations National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa, SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu Natal, Durban, South Africa

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• Carolyn Williamson ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Software, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Institute for Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa, Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu Natal, Durban, South Africa, National Health Laboratory Service, Cape Town, South Africa

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•  [ ... ],
• Lynn Morris

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa, SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu Natal, Durban, South Africa

  https://orcid.org/0000-0003-3961-7828

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