Impact of stabilizing mutations on the antigenic profile and glycosylation of membrane-expressed HIV-1 envelope glycoprotein

Tommy Tong; Alessio D’Addabbo; Jiamin Xu; Himanshi Chawla; Albert Nguyen; Paola Ochoa; Max Crispin; James M. Binley

doi:10.1371/journal.ppat.1011452

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Open Access

Peer-reviewed

Research Article

Impact of stabilizing mutations on the antigenic profile and glycosylation of membrane-expressed HIV-1 envelope glycoprotein

Tommy Tong,

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing

Affiliation San Diego Biomedical Research Institute, San Diego, California, United States of America
⨯
Alessio D’Addabbo,

Roles Data curation, Formal analysis, Investigation, Software, Visualization

Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
⨯
Jiamin Xu,

Roles Data curation, Investigation, Software, Writing – review & editing

Affiliation San Diego Biomedical Research Institute, San Diego, California, United States of America
⨯
Himanshi Chawla,

Roles Investigation

Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
⨯
Albert Nguyen,

Roles Data curation, Visualization

Affiliation San Diego Biomedical Research Institute, San Diego, California, United States of America
⨯
Paola Ochoa,

Roles Data curation, Visualization

Affiliation San Diego Biomedical Research Institute, San Diego, California, United States of America
⨯
Max Crispin,

Roles Data curation, Funding acquisition, Investigation, Supervision, Visualization

Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
⨯
James M. Binley

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: jbinley@sdbri.org

Affiliation San Diego Biomedical Research Institute, San Diego, California, United States of America

https://orcid.org/0000-0001-5032-6111

⨯

Impact of stabilizing mutations on the antigenic profile and glycosylation of membrane-expressed HIV-1 envelope glycoprotein

Tommy Tong,
Alessio D’Addabbo,
Jiamin Xu,
Himanshi Chawla,
Albert Nguyen,
Paola Ochoa,
Max Crispin,
James M. Binley

Published: August 7, 2023
https://doi.org/10.1371/journal.ppat.1011452

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