Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system

• Marine Blanc,

  Roles Investigation, Writing – original draft

  Affiliation UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France

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• Clara Lettl,

  Roles Investigation

  Affiliation Max von Pettenkofer Institute of Hygiene and Medical Microbiology, Faculty of Medicine, LMU Munich, Munich, Germany

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• Jérémy Guérin,

  Roles Investigation

  Affiliation UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France

  https://orcid.org/0000-0002-7123-6892

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• Anaïs Vieille,

  Roles Investigation

  Affiliation UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France

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• Sven Furler,

  Roles Investigation

  Affiliation Department of Biochemistry, University of Zurich, Zurich, Switzerland

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• Sylvie Briand-Schumacher,

  Roles Investigation

  Affiliation Department of Biochemistry, University of Zurich, Zurich, Switzerland

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• Birgit Dreier,

  Roles Investigation

  Affiliation Department of Biochemistry, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0002-5124-9346

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• Célia Bergé,

  Roles Investigation

  Affiliation UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France

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• Andreas Plückthun,

  Roles Conceptualization, Formal analysis, Funding acquisition, Writing – review & editing

  Affiliation Department of Biochemistry, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0003-4191-5306

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• Sandrine Vadon-Le Goff,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation University of Lyon, CNRS UMR5305, Tissue Biology and Therapeutic Engineering Laboratory (LBTI), Lyon, France

  https://orcid.org/0000-0002-4582-2273

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• Rémi Fronzes,

  Roles Funding acquisition, Investigation

  Affiliation European Institute of Chemistry and Biology, CNRS UMR 5234 Microbiologie Fondamentale et Pathogénicité, Univ. Bordeaux, Pessac, France

  https://orcid.org/0000-0003-3031-9824

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• Patricia Rousselle,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Writing – review & editing

  Affiliation University of Lyon, CNRS UMR5305, Tissue Biology and Therapeutic Engineering Laboratory (LBTI), Lyon, France

  https://orcid.org/0000-0003-0275-4562

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• Wolfgang Fischer ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Writing – review & editing

  * E-mail: Fischer@mvp.lmu.de (WF); laurent.terradot@ibcp.fr (LT)

  Affiliation Max von Pettenkofer Institute of Hygiene and Medical Microbiology, Faculty of Medicine, LMU Munich, Munich, Germany

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• Laurent Terradot

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

  * E-mail: Fischer@mvp.lmu.de (WF); laurent.terradot@ibcp.fr (LT)

  Affiliation UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France

  https://orcid.org/0000-0003-4279-9167

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