Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae

• Paeton L. Wantuch,

  Roles Conceptualization, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliation Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, Missouri, United States of America

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• Cory J. Knoot,

  Roles Investigation, Methodology

  Affiliation Omniose, Saint Louis, Missouri, United States of America

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• Lloyd S. Robinson,

  Roles Investigation, Methodology

  Affiliation Omniose, Saint Louis, Missouri, United States of America

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• Evgeny Vinogradov,

  Roles Investigation, Methodology, Validation

  Affiliation National Research Council Canada, Human Health Therapeutics Centre, Ottawa, Ontario, Canada

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• Nichollas E. Scott,

  Roles Investigation, Methodology, Validation

  Affiliation Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia

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• Christian M. Harding ,

  Roles Conceptualization, Methodology, Supervision, Writing – original draft

  * E-mail: christian.harding@omniose.com (CMH); rosend@wustl.edu (DAR)

  Affiliation Omniose, Saint Louis, Missouri, United States of America

  https://orcid.org/0000-0002-2158-3546

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• David A. Rosen

  Roles Conceptualization, Methodology, Supervision, Writing – original draft

  * E-mail: christian.harding@omniose.com (CMH); rosend@wustl.edu (DAR)

  Affiliations Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, Missouri, United States of America, Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America

  https://orcid.org/0000-0003-1081-772X

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