Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2

• Gary Ewart ,

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  * E-mail: gewart@biotron.com.au

  Affiliation Biotron Limited, North Ryde, New South Wales, Australia

  https://orcid.org/0000-0001-5919-8275

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• Michael Bobardt,

  Roles Data curation, Investigation, Methodology

  Affiliation The Scripps Institute, Immunology and Microbiology, La Jolla, California, United States of America

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• Bo Hjorth Bentzen,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation University of Copenhagen, Department of Biomedical Sciences, Copenhagen, Denmark

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• Yannan Yan,

  Roles Investigation

  Affiliation University of Copenhagen, Department of Biomedical Sciences, Copenhagen, Denmark

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• Audrey Thomson,

  Roles Project administration, Writing – original draft

  Affiliation Biotron Limited, North Ryde, New South Wales, Australia

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• Klaus Klumpp,

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Biotron Limited, North Ryde, New South Wales, Australia

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• Stephen Becker,

  Roles Writing – review & editing

  Affiliation Biotron Limited, North Ryde, New South Wales, Australia

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• Mette M. Rosenkilde,

  Roles Conceptualization, Data curation, Investigation, Writing – review & editing

  Affiliation University of Copenhagen, Department of Biomedical Sciences, Copenhagen, Denmark

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• Michelle Miller,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  Affiliation Biotron Limited, North Ryde, New South Wales, Australia

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• Philippe Gallay

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration

  Affiliation The Scripps Institute, Immunology and Microbiology, La Jolla, California, United States of America

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