Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection

• Mason R. Firpo,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America

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• Natalie J. LoMascolo,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliations Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America, Infectious Disease and Immunology Research Institute, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America

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• Marine J. Petit,

  Roles Investigation, Methodology, Software, Visualization, Writing – review & editing

  Current address: University of Glasgow MRC-Center for virus research, Glasgow, United Kingdom

  Affiliations Department of Microbiology and Molecular Genetics, University of California, Davis, Davis, California, United States of America, Department of Chemical Engineering, University of California, Davis, Davis, California, United States of America

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• Priya S. Shah,

  Roles Funding acquisition, Methodology, Software, Supervision, Writing – review & editing

  Affiliations Department of Microbiology and Molecular Genetics, University of California, Davis, Davis, California, United States of America, Department of Chemical Engineering, University of California, Davis, Davis, California, United States of America

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• Bryan C. Mounce

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bmounce@luc.edu

  Affiliations Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America, Infectious Disease and Immunology Research Institute, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America

  https://orcid.org/0000-0003-1710-5362

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