Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination

• Jacob E. Lemieux ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lemieux@broadinstitute.org

  Affiliations Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0002-2758-4005

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• Weihua Huang,

  Roles Formal analysis, Methodology, Software, Writing – review & editing

  Affiliations New York Medical College, Valhalla, New York, United States of America, East Carolina University, Greenville, North Carolina, United States of America

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• Nathan Hill,

  Roles Data curation, Investigation, Project administration, Writing – review & editing

  Affiliations Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Tjasa Cerar,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation University of Ljubljana, Ljubljana, Slovenia

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• Lisa Freimark,

  Roles Investigation, Writing – review & editing

  Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Sergio Hernandez,

  Roles Investigation, Writing – review & editing

  Affiliation Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

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• Matteo Luban,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliations Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Vera Maraspin,

  Roles Investigation, Writing – review & editing

  Affiliation University Medical Center Ljubljana, Ljubljana, Slovenia

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• Petra Bogovič,

  Roles Investigation, Writing – review & editing

  Affiliation University Medical Center Ljubljana, Ljubljana, Slovenia

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• Katarina Ogrinc,

  Roles Investigation, Writing – review & editing

  Affiliation University Medical Center Ljubljana, Ljubljana, Slovenia

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• Eva Ruzič-Sabljič,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation University of Ljubljana, Ljubljana, Slovenia

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• Pascal Lapierre,

  Roles Investigation, Writing – review & editing

  Affiliation Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

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• Erica Lasek-Nesselquist,

  Roles Investigation, Writing – review & editing

  Affiliation Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

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• Navjot Singh,

  Roles Investigation, Writing – review & editing

  Affiliation Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

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• Radha Iyer,

  Roles Investigation, Writing – review & editing

  Affiliation New York Medical College, Valhalla, New York, United States of America

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• Dionysios Liveris,

  Roles Investigation, Writing – review & editing

  Affiliation New York Medical College, Valhalla, New York, United States of America

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• Kurt D. Reed,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation University of Wisconsin, Madison, Wisconsin, United States of America

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• John M. Leong,

  Roles Investigation, Writing – review & editing

  Affiliation Tufts University School of Medicine, Boston, Massachusetts, United States of America

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• John A. Branda,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Allen C. Steere,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Gary P. Wormser,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation New York Medical College, Valhalla, New York, United States of America

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• Franc Strle,

  Roles Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliation University Medical Center Ljubljana, Ljubljana, Slovenia

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• Pardis C. Sabeti ,

  Contributed equally to this work with: Pardis C. Sabeti, Ira Schwartz, Klemen Strle

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – review & editing

  Affiliations Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Harvard University, Cambridge, Massachusetts, United States of America, Harvard T.H.Chan School of Public Health, Boston, Massachusetts, United States of America

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• Ira Schwartz ,

  Contributed equally to this work with: Pardis C. Sabeti, Ira Schwartz, Klemen Strle

  Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

  Affiliation New York Medical College, Valhalla, New York, United States of America

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•  [ ... ],
• Klemen Strle

  Contributed equally to this work with: Pardis C. Sabeti, Ira Schwartz, Klemen Strle

  Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

  Affiliations Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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