Potent NKT cell ligands overcome SARS-CoV-2 immune evasion to mitigate viral pathogenesis in mouse models

• Hongjia Lu ,

  Contributed equally to this work with: Hongjia Lu, Zhewei Liu, Xiangxue Deng

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – review & editing

  Affiliations Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America, Graduate Programs in Biomedical and Biological Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Zhewei Liu ,

  Contributed equally to this work with: Hongjia Lu, Zhewei Liu, Xiangxue Deng

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – review & editing

  Current address: Graduate Program in Fundamental Immunology, Department of Immunology, University of Toronto, Toronto, Ontario, Canada

  Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Xiangxue Deng ,

  Contributed equally to this work with: Hongjia Lu, Zhewei Liu, Xiangxue Deng

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – review & editing

  Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Siyang Chen,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – review & editing

  Current address: Shanghai Micropot Medical Co., Pudong New District, Shanghai, China

  Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Ruiting Zhou,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Current address: Cleveland Clinic Florida Research and Innovation Center, Port St. Lucie, Florida, United States of America

  Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Rongqi Zhao,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Current address: RAPT Therapeutics, Inc., South San Francisco, California, United States of America

  Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Ramya Parandaman,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Amarjot Thind,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Jill Henley,

  Roles Data curation, Investigation, Methodology, Validation, Visualization

  Affiliation The Hastings and Wright Laboratories, Keck School of Medicine, University Southern California, California, United States of America

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• Lei Tian,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Los Angeles, California, United States of America

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• Jianhua Yu,

  Roles Methodology

  Affiliation Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Los Angeles, California, United States of America

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• Lucio Comai,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliations Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America, The Hastings and Wright Laboratories, Keck School of Medicine, University Southern California, California, United States of America

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• Pinghui Feng,

  Roles Investigation, Resources

  Affiliation Section of Infection and Immunity, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California, United States of America

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• Weiming Yuan

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: weiming.yuan@usc.edu

  Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

  https://orcid.org/0000-0002-4780-7157

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