The anti-immune dengue subgenomic flaviviral RNA is present in vesicles in mosquito saliva and is associated with increased infectivity

• Shih-Chia Yeh ,

  Contributed equally to this work with: Shih-Chia Yeh, Tania Strilets

  Roles Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Current address: Cancer Science Institute of Singapore, National University of Singapore, Singapore

  Affiliation Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore

  ⨯
• Tania Strilets ,

  Contributed equally to this work with: Shih-Chia Yeh, Tania Strilets

  Roles Formal analysis, Funding acquisition, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America

  ⨯
• Wei-Lian Tan,

  Roles Investigation, Writing – original draft, Writing – review & editing

  Affiliation Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore

  ⨯
• David Castillo,

  Roles Formal analysis

  Affiliation CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

  ⨯
• Hacène Medkour,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation MIVEGEC, Univ. Montpellier, IRD, CNRS, Montpellier, France

  ⨯
• Félix Rey-Cadilhac,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation MIVEGEC, Univ. Montpellier, IRD, CNRS, Montpellier, France

  ⨯
• Idalba M. Serrato-Pomar,

  Roles Investigation, Writing – review & editing

  Affiliation MIVEGEC, Univ. Montpellier, IRD, CNRS, Montpellier, France

  ⨯
• Florian Rachenne,

  Roles Investigation, Writing – review & editing

  Affiliation MIVEGEC, Univ. Montpellier, IRD, CNRS, Montpellier, France

  ⨯
• Avisha Chowdhury,

  Roles Investigation, Writing – review & editing

  Current address: Toronto Centre for Liver Disease, University Health Network, Princess Margaret Cancer Research Tower, Toronto, Canada

  Affiliation Department of Biological Sciences, National University of Singapore, Singapore

  ⨯
• Vanessa Chuo,

  Roles Investigation, Writing – review & editing

  Affiliation Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore

  ⨯
• Sasha R. Azar,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

  ⨯
• Moirangthem Kiran Singh,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America

  ⨯
• Rodolphe Hamel,

  Roles Investigation, Writing – review & editing

  Affiliation MIVEGEC, Univ. Montpellier, IRD, CNRS, Montpellier, France

  ⨯
• Dorothée Missé,

  Roles Formal analysis, Writing – review & editing

  Affiliation MIVEGEC, Univ. Montpellier, IRD, CNRS, Montpellier, France

  ⨯
• R. Manjunatha Kini,

  Roles Funding acquisition, Writing – review & editing

  Affiliations Department of Biological Sciences, National University of Singapore, Singapore, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

  ⨯
• Linda J. Kenney,

  Roles Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America

  ⨯
• Nikos Vasilakis,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America, Center for Biodefense and Emerging Infectious Diseases, University of University of Texas Medical Branch, Galveston, Texas, United States of America, Center for Tropical Diseases, University of University of Texas Medical Branch, Galveston, Texas, United States of America, Institute for Human Infection and Immunity, University of University of Texas Medical Branch, Galveston, Texas, United States of America, Center for Vector-Borne and Zoonotic Diseases, University of University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Preventive Medicine and Population Health, University of University of Texas Medical Branch, Galveston, Texas, United States of America, World Reference Center for Emerging Viruses and Arboviruses, University of University of Texas Medical Branch, Galveston, Texas, United States of America

  ⨯
• Marc A. Marti-Renom,

  Roles Formal analysis, Writing – review & editing

  Affiliations CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain, Universitat Pompeu Fabra (UPF), Barcelona, Spain, ICREA, Barcelona, Spain

  ⨯
• Guy Nir,

  Roles Formal analysis, Funding acquisition, Project administration, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America

  ⨯
• Julien Pompon ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: julien.pompon@ird.fr (JP); marianogb@virginia.edu, maragarc@utmb.edu (MAGB)

  ¶‡ JP and MAG-B also contributed equally to this work.

  Affiliations Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, MIVEGEC, Univ. Montpellier, IRD, CNRS, Montpellier, France

  ⨯
•  [ ... ],
• Mariano A. Garcia-Blanco

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: julien.pompon@ird.fr (JP); marianogb@virginia.edu, maragarc@utmb.edu (MAGB)

  ¶‡ JP and MAG-B also contributed equally to this work.

  Affiliations Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America

  https://orcid.org/0000-0001-8538-1997

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