Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes

• Paradise Madlala ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: madlalap@ukzn.ac.za.

  Affiliations HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa

  https://orcid.org/0000-0003-0641-1452

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• Zakithi Mkhize,

  Roles Data curation, Writing – review & editing

  Affiliation HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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• Shamara Naicker,

  Roles Data curation, Writing – review & editing

  Affiliation HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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• Samukelisiwe P. Khathi,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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• Shreyal Maikoo,

  Roles Formal analysis, Writing – review & editing

  Affiliation HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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• Kasmira Gopee,

  Roles Formal analysis, Writing – review & editing

  Affiliation HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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• Krista L. Dong,

  Roles Data curation, Writing – review & editing

  Affiliations Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America, Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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• Thumbi Ndung’u

  Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing

  Affiliations HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America, Africa Health Research Institute (AHRI), Durban, South Africa, Division of Infection and Immunity, University College London, London, United Kingdom

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