Antagonism of ALAS1 by the Measles Virus V protein contributes to degradation of the mitochondrial network and promotes interferon response

• Pierre Khalfi ,

  Contributed equally to this work with: Pierre Khalfi, Rodolphe Suspène

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliations Virus and Cellular Stress Unit, Department of Virology, Institut Pasteur, Université de Paris Cité, Paris, France, Sorbonne Université, Complexité du Vivant, ED515, Paris, France

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• Rodolphe Suspène ,

  Contributed equally to this work with: Pierre Khalfi, Rodolphe Suspène

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliation Virus and Cellular Stress Unit, Department of Virology, Institut Pasteur, Université de Paris Cité, Paris, France

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• Kyle A. Raymond,

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliations Virus and Cellular Stress Unit, Department of Virology, Institut Pasteur, Université de Paris Cité, Paris, France, Sorbonne Université, Complexité du Vivant, ED515, Paris, France

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• Vincent Caval,

  Roles Formal analysis, Methodology

  Current address: Virus Sensing and Signaling, Institut Pasteur, Université de Paris Cité, Paris, France

  Affiliation Virus and Cellular Stress Unit, Department of Virology, Institut Pasteur, Université de Paris Cité, Paris, France

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• Grégory Caignard,

  Roles Formal analysis, Methodology, Validation

  Affiliation UMR1161 Virologie, ANSES-INRAE-ENVA, Maisons-Alfort, France

  ⨯
• Noémie Berry,

  Roles Methodology

  Affiliations Virus and Cellular Stress Unit, Department of Virology, Institut Pasteur, Université de Paris Cité, Paris, France, Sorbonne Université, Complexité du Vivant, ED515, Paris, France, UMR1161 Virologie, ANSES-INRAE-ENVA, Maisons-Alfort, France

  ⨯
• Valérie Thiers,

  Roles Methodology

  Affiliation Virus and Cellular Stress Unit, Department of Virology, Institut Pasteur, Université de Paris Cité, Paris, France

  ⨯
• Chantal Combredet,

  Roles Methodology

  Affiliation Vaccines Innovation Laboratory, Institut Pasteur, Université de Paris Cité, Paris, France

  ⨯
• Claude Rufie,

  Roles Methodology

  Affiliation Vaccines Innovation Laboratory, Institut Pasteur, Université de Paris Cité, Paris, France

  ⨯
• Stéphane Rigaud,

  Roles Methodology, Validation

  Affiliation Image Analysis Hub, Institut Pasteur, Université de Paris Cité, Paris, France

  ⨯
• Amine Ghozlane,

  Roles Methodology, Validation

  Affiliation Bioinformatics and Biostatistics HUB, Institut Pasteur, Université de Paris Cité, Paris, France

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• Stevenn Volant,

  Roles Methodology, Validation

  Affiliation Bioinformatics and Biostatistics HUB, Institut Pasteur, Université de Paris Cité, Paris, France

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• Anastassia V. Komarova,

  Roles Methodology, Validation

  Affiliation Interactomics, RNA and Immunity Laboratory, Institut Pasteur, Université de Paris Cité, Paris, France

  ⨯
• Frédéric Tangy,

  Roles Formal analysis, Validation

  Affiliation Vaccines Innovation Laboratory, Institut Pasteur, Université de Paris Cité, Paris, France

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• Jean-Pierre Vartanian

  Roles Conceptualization, Formal analysis, Supervision, Validation, Writing – original draft

  * E-mail: jean-pierre.vartanian@pasteur.fr

  Affiliation Virus and Cellular Stress Unit, Department of Virology, Institut Pasteur, Université de Paris Cité, Paris, France

  https://orcid.org/0000-0001-8079-8814

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