Berberine governs NOTCH3/AKT signaling to enrich lung-resident memory T cells during tuberculosis

Isha Pahuja; Kriti Negi; Anjna Kumari; Meetu Agarwal; Suparba Mukhopadhyay; Babu Mathew; Shivam Chaturvedi; Jaswinder Singh Maras; Ashima Bhaskar; Ved Prakash Dwivedi

doi:10.1371/journal.ppat.1011165

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Open Access

Peer-reviewed

Research Article

Berberine governs NOTCH3/AKT signaling to enrich lung-resident memory T cells during tuberculosis

Isha Pahuja ,

Contributed equally to this work with: Isha Pahuja, Kriti Negi

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

Affiliations Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India, Department of Molecular Medicine, Jamia Hamdard University, New Delhi, India
⨯
Kriti Negi ,

Contributed equally to this work with: Isha Pahuja, Kriti Negi

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

Affiliation Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Anjna Kumari,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Meetu Agarwal,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Molecular Medicine, Jamia Hamdard University, New Delhi, India
⨯
Suparba Mukhopadhyay,

Roles Data curation, Formal analysis, Methodology

Affiliation Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Babu Mathew,

Roles Data curation, Formal analysis, Methodology

Affiliation Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi, India
⨯
Shivam Chaturvedi,

Roles Data curation, Formal analysis, Methodology

Affiliation Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Jaswinder Singh Maras,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi, India
⨯
Ashima Bhaskar ,

Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ashimabhaskar23@gmail.com (AB); vedprakashbt@gmail.com (VPD)

Affiliation Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
⨯
Ved Prakash Dwivedi

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ashimabhaskar23@gmail.com (AB); vedprakashbt@gmail.com (VPD)

Affiliation Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India

https://orcid.org/0000-0003-4321-2567

⨯

Berberine governs NOTCH3/AKT signaling to enrich lung-resident memory T cells during tuberculosis

Isha Pahuja,
Kriti Negi,
Anjna Kumari,
Meetu Agarwal,
Suparba Mukhopadhyay,
Babu Mathew,
Shivam Chaturvedi,
Jaswinder Singh Maras,
Ashima Bhaskar,
Ved Prakash Dwivedi

Published: March 7, 2023
https://doi.org/10.1371/journal.ppat.1011165

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