Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection

• Xiaoyuan Lin ,

  Contributed equally to this work with: Xiaoyuan Lin, Beibei Fu

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliations School of Life Sciences, Chongqing University, Chongqing, China, Institut für Virologie, Freie Universität Berlin, Berlin, Germany

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• Beibei Fu ,

  Contributed equally to this work with: Xiaoyuan Lin, Beibei Fu

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation School of Life Sciences, Chongqing University, Chongqing, China

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• Yan Xiong,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation School of Life Sciences, Chongqing University, Chongqing, China

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• Na Xing,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Institut für Virologie, Freie Universität Berlin, Berlin, Germany

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• Weiwei Xue,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation School of Pharmaceutical Sciences, Chongqing University, Chongqing, China

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• Dong Guo,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation School of Life Sciences, Chongqing University, Chongqing, China

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• Mohamed Zaky,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Molecular Physiology Division, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt

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• Krishna Pavani,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Reproduction, Obstetrics and Herd Health, Ghent University, Merelbeke, Belgium

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• Dusan Kunec,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Institut für Virologie, Freie Universität Berlin, Berlin, Germany

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• Jakob Trimpert,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliation Institut für Virologie, Freie Universität Berlin, Berlin, Germany

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• Haibo Wu

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: hbwu023@cqu.edu.cn

  Affiliation School of Life Sciences, Chongqing University, Chongqing, China

  https://orcid.org/0000-0002-5961-2947

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