Fn-Dps, a novel virulence factor of Fusobacterium nucleatum, disrupts erythrocytes and promotes metastasis in colorectal cancer

Yixian Wu; Songhe Guo; Fangfang Chen; Yiqiu Li; Yuying Huang; Wanli Liu; Ge Zhang

doi:10.1371/journal.ppat.1011096

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Open Access

Peer-reviewed

Research Article

Fn-Dps, a novel virulence factor of Fusobacterium nucleatum, disrupts erythrocytes and promotes metastasis in colorectal cancer

Yixian Wu ,

Contributed equally to this work with: Yixian Wu, Songhe Guo

Roles Data curation, Formal analysis, Investigation, Validation, Writing – original draft

Affiliation Department of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Songhe Guo ,

Contributed equally to this work with: Yixian Wu, Songhe Guo

Roles Data curation, Formal analysis, Funding acquisition, Writing – original draft

Affiliation State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China
⨯
Fangfang Chen,

Roles Data curation, Methodology, Validation

Affiliation Department of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Yiqiu Li,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Yuying Huang,

Roles Resources

Affiliation Department of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Wanli Liu ,

Roles Formal analysis, Resources, Writing – review & editing

* E-mail: aliuwl@sysucc.org.cn (WL); zhangge@mail.sysu.edu.cn (GZ)

Affiliation State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China
⨯
Ge Zhang

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: aliuwl@sysucc.org.cn (WL); zhangge@mail.sysu.edu.cn (GZ)

Affiliation Department of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China

https://orcid.org/0000-0002-2316-963X

⨯

Fn-Dps, a novel virulence factor of Fusobacterium nucleatum, disrupts erythrocytes and promotes metastasis in colorectal cancer

Yixian Wu,
Songhe Guo,
Fangfang Chen,
Yiqiu Li,
Yuying Huang,
Wanli Liu,
Ge Zhang

Published: January 24, 2023
https://doi.org/10.1371/journal.ppat.1011096

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Enzyme-linked immunoassays
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