Structure-guided mutagenesis of the capsid protein indicates that a nanovirus requires assembled viral particles for systemic infection

• Stefano Trapani ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: stefano.trapani@cbs.cnrs.fr (ST); stephane.blanc@inrae.fr (SB); patrick.bron@cbs.cnrs.fr (PB)

  Affiliation CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, INSERM, Montpellier, France

  https://orcid.org/0000-0002-2929-6306

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• Eijaz Ahmed Bhat,

  Roles Investigation

  Affiliation CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, INSERM, Montpellier, France

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• Michel Yvon,

  Roles Investigation

  Affiliation PHIM, INRAE, CIRAD, IRD, SupAgro, Univ Montpellier, Montpellier, France

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• Joséphine Lai-Kee-Him,

  Roles Investigation

  Affiliation CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, INSERM, Montpellier, France

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• François Hoh,

  Roles Investigation

  Affiliation CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, INSERM, Montpellier, France

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• Marie-Stéphanie Vernerey,

  Roles Investigation

  Affiliation PHIM, INRAE, CIRAD, IRD, SupAgro, Univ Montpellier, Montpellier, France

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• Elodie Pirolles,

  Roles Investigation

  Affiliation PHIM, INRAE, CIRAD, IRD, SupAgro, Univ Montpellier, Montpellier, France

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• Mélia Bonnamy,

  Roles Investigation

  Affiliation PHIM, INRAE, CIRAD, IRD, SupAgro, Univ Montpellier, Montpellier, France

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• Guy Schoehn,

  Roles Resources, Writing – review & editing

  Affiliation Univ. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France

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• Jean-Louis Zeddam,

  Roles Conceptualization, Investigation, Validation, Writing – review & editing

  Affiliation PHIM, INRAE, CIRAD, IRD, SupAgro, Univ Montpellier, Montpellier, France

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• Stéphane Blanc ,

  Contributed equally to this work with: Stéphane Blanc, Patrick Bron

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: stefano.trapani@cbs.cnrs.fr (ST); stephane.blanc@inrae.fr (SB); patrick.bron@cbs.cnrs.fr (PB)

  Affiliation PHIM, INRAE, CIRAD, IRD, SupAgro, Univ Montpellier, Montpellier, France

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• Patrick Bron

  Contributed equally to this work with: Stéphane Blanc, Patrick Bron

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: stefano.trapani@cbs.cnrs.fr (ST); stephane.blanc@inrae.fr (SB); patrick.bron@cbs.cnrs.fr (PB)

  Affiliation CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, INSERM, Montpellier, France

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