Natural product ligands of FKBP12: Immunosuppressive antifungal agents FK506, rapamycin, and beyond

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Angela Rivera ,

* E-mail: angela.rivera@duke.edu

Affiliation Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America

https://orcid.org/0000-0003-0827-0788

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Joseph Heitman

Affiliations Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
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Immunosuppressives
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Crystal structure
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Saccharomyces cerevisiae
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Antifungals
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Fungal pathogens
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Fungal structure
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T cells
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Streptomyces
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