Immunopeptidome profiling of human coronavirus OC43-infected cells identifies CD4 T-cell epitopes specific to seasonal coronaviruses or cross-reactive with SARS-CoV-2

• Aniuska Becerra-Artiles ,

  Contributed equally to this work with: Aniuska Becerra-Artiles, Padma P. Nanaware

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester Massachusetts, United States of America

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• Padma P. Nanaware ,

  Contributed equally to this work with: Aniuska Becerra-Artiles, Padma P. Nanaware

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester Massachusetts, United States of America

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• Khaja Muneeruddin,

  Roles Methodology

  Affiliation Mass Spectrometry Facility, UMass Chan Medical School, Shrewsbury Massachusetts, United States of America

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• Grant C. Weaver,

  Roles Investigation

  Affiliation Department of Pathology, Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester Massachusetts, United States of America

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• Scott A. Shaffer,

  Roles Methodology, Writing – review & editing

  Affiliations Mass Spectrometry Facility, UMass Chan Medical School, Shrewsbury Massachusetts, United States of America, Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, Massachusetts, United States of America

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• J. Mauricio Calvo-Calle,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester Massachusetts, United States of America

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• Lawrence J. Stern

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lawrence.stern@umassmed.edu

  Affiliations Department of Pathology, Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester Massachusetts, United States of America, Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, Massachusetts, United States of America

  https://orcid.org/0000-0001-9870-8557

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