ROP39 is an Irgb10-specific parasite effector that modulates acute Toxoplasma gondii virulence

• Shishir Singh ,

  Contributed equally to this work with: Shishir Singh, Mateo Murillo-León

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Faculty of Biology, University of Freiburg, Freiburg, Germany

  https://orcid.org/0000-0002-8488-3992

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• Mateo Murillo-León ,

  Contributed equally to this work with: Shishir Singh, Mateo Murillo-León

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Faculty of Biology, University of Freiburg, Freiburg, Germany

  https://orcid.org/0000-0003-3462-3612

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• Niklas Sebastian Endres,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Faculty of Biology, University of Freiburg, Freiburg, Germany

  https://orcid.org/0000-0001-5093-1020

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• Ailan Farid Arenas Soto,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Grupo GEPAMOL, Centro de Investigaciones Biomedicas, Universidad del Quindio, Armenia, Quindio, Colombia

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• Jorge Enrique Gómez-Marín,

  Roles Formal analysis, Writing – review & editing

  Affiliation Grupo GEPAMOL, Centro de Investigaciones Biomedicas, Universidad del Quindio, Armenia, Quindio, Colombia

  https://orcid.org/0000-0001-6472-3329

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• Florence Melbert,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany, Faculty of Biology, University of Freiburg, Freiburg, Germany

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• Thirumala-Devi Kanneganti,

  Roles Resources, Writing – review & editing

  Affiliation Department of Immunology, St. Jude Children´s Research Hospital, Memphis, Tenessee, United States of America

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• Masahiro Yamamoto,

  Roles Resources, Writing – review & editing

  Affiliations Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan, Laboratory of Immunoparasitology, World Premier International Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan

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• Claudia Campos,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Fundacao Calouste Gulbekian, Instituto Gulbekian de Ciencia, Oeiras, Portugal

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• Jonathan Charles Howard,

  Roles Formal analysis, Resources, Writing – review & editing

  Affiliation Fundacao Calouste Gulbekian, Instituto Gulbekian de Ciencia, Oeiras, Portugal

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• Gregory Alan Taylor,

  Roles Resources, Writing – review & editing

  Affiliations Departments of Medicine; Molecular Genetics and Microbiology; and Immunology; and Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, United States of America, Geriatric Research, Education, and Clinical Center, Durham VA Health Care System, Durham, North Carolina, United States of America

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• Tobias Steinfeldt

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: tobias.steinfeldt@uniklinik-freiburg.de

  Affiliations Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany, Faculty of Medicine, University of Freiburg, Freiburg, Germany

  https://orcid.org/0000-0002-1975-5513

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