High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire

• Iga Kucharska,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada

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• Špela Binter,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Visualization, Writing – review & editing

  Affiliation Kymab Ltd., The Bennet Building (B930) Babraham Research Campus, Cambridge, United Kingdom

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• Rajagopal Murugan,

  Roles Investigation, Methodology, Writing – review & editing

  Current address: Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands

  Affiliation B Cell Immunology, German Cancer Research Institute (DKFZ), Heidelberg, Germany

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• Stephen W. Scally,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliation Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada

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• Julia Ludwig,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation B Cell Immunology, German Cancer Research Institute (DKFZ), Heidelberg, Germany

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• Katherine Prieto,

  Roles Investigation, Methodology

  Affiliation Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada

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• Elaine Thai,

  Roles Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliations Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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• Giulia Costa,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Vector Biology Unit, Max Planck Institute for Infection Biology, Berlin, Germany

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• Kan Li,

  Roles Investigation, Methodology

  Affiliation Department of Surgery, Immunology, Molecular Genetics and Microbiology, Center for Human Systems Immunology, Duke University, Durham, North Carolina, United States of America

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• Gillian Q. Horn,

  Roles Investigation, Methodology

  Affiliation Department of Surgery, Immunology, Molecular Genetics and Microbiology, Center for Human Systems Immunology, Duke University, Durham, North Carolina, United States of America

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• Yevel Flores-Garcia,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Molecular Microbiology and Immunology, Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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• Alexandre Bosch,

  Roles Investigation, Methodology

  Affiliation Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada

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• Taylor Sicard,

  Roles Conceptualization, Investigation

  Affiliations Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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• John L. Rubinstein,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliations Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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• Fidel Zavala,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Molecular Microbiology and Immunology, Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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• S. Moses Dennison,

  Roles Project administration, Supervision, Writing – review & editing

  Affiliation Department of Surgery, Immunology, Molecular Genetics and Microbiology, Center for Human Systems Immunology, Duke University, Durham, North Carolina, United States of America

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• Georgia D. Tomaras,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Surgery, Immunology, Molecular Genetics and Microbiology, Center for Human Systems Immunology, Duke University, Durham, North Carolina, United States of America

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• Elena A. Levashina,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Vector Biology Unit, Max Planck Institute for Infection Biology, Berlin, Germany

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• Paul Kellam,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Kymab Ltd., The Bennet Building (B930) Babraham Research Campus, Cambridge, United Kingdom, Department of Infectious Diseases, Faculty of Medicine, Imperial College London, London, United Kingdom

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• Hedda Wardemann,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation B Cell Immunology, German Cancer Research Institute (DKFZ), Heidelberg, Germany

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•  [ ... ],
• Jean-Philippe Julien

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: jean-philippe.julien@sickkids.ca

  Affiliations Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada, Department of Immunology, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0001-7602-3995

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