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Open Access
Peer-reviewed
Research Article
Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA
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Jens Kleinehr,
Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Michael Schöfbänker,
Roles Investigation
Affiliation Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Katharina Daniel,
Roles Investigation
Affiliation Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Franziska Günl,
Roles Methodology, Resources
Affiliation Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Fakry Fahmy Mohamed,
Roles Investigation
Affiliations Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany, Department of Virology, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Egypt
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Josua Janowski,
Roles Investigation, Resources
Affiliation Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Linda Brunotte,
Roles Funding acquisition, Resources
Affiliation Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Yvonne Boergeling,
Roles Investigation, Methodology
Affiliation Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Marie Liebmann,
Roles Investigation, Methodology
Affiliation Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, Muenster, Germany
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Matthias Behrens,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliation Institute of Food Chemistry, Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Andrea Gerdemann,
Roles Data curation, Formal analysis, Investigation
Affiliation Institute of Food Chemistry, Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Luisa Klotz,
Roles Resources
Affiliation Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, Muenster, Germany
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Melanie Esselen,
Roles Resources
Affiliation Institute of Food Chemistry, Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Hans-Ulrich Humpf,
Roles Resources
Affiliation Institute of Food Chemistry, Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Stephan Ludwig ,
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: ludwigs@uni-muenster.de
¶‡ These authors are joint senior authors on this work.
Affiliation Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Eike R. Hrincius
Roles Conceptualization, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing
¶‡ These authors are joint senior authors on this work.
Affiliation Institute of Virology Muenster (IVM), Westfaelische Wilhelms-University Muenster, Muenster, Germany
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Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA
- Jens Kleinehr,
- Michael Schöfbänker,
- Katharina Daniel,
- Franziska Günl,
- Fakry Fahmy Mohamed,
- Josua Janowski,
- Linda Brunotte,
- Yvonne Boergeling,
- Marie Liebmann,
- Matthias Behrens
- Published: July 13, 2023
- https://doi.org/10.1371/journal.ppat.1010986