Progranulin aggravates lethal Candida albicans sepsis by regulating inflammatory response and antifungal immunity

• Jiayu Liu ,

  Contributed equally to this work with: Jiayu Liu, Xiaofei Lai

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, School of Laboratory Medicine, Chongqing Medical University, Chongqing, China

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• Xiaofei Lai ,

  Contributed equally to this work with: Jiayu Liu, Xiaofei Lai

  Roles Formal analysis, Investigation, Methodology, Project administration, Resources, Writing – review & editing

  Affiliation Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Renlin Yu,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Hao Ding,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Haobo Bai,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Zhubin Yang,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Yibing Yin,

  Roles Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, School of Laboratory Medicine, Chongqing Medical University, Chongqing, China

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• Fang Xu,

  Roles Formal analysis, Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Department of Intensive Care Unit, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Ju Cao

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: caoju723@163.com

  Affiliation Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

  https://orcid.org/0000-0002-4855-6986

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