Binding of adenovirus species C hexon to prothrombin and the influence of hexon on vector properties in vitro and in vivo

• Jie Tian,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Division of Cellular and Gene Therapies, FDA Center for Biologics Evaluation and Research, Silver Spring, Maryland, United States of America

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• Zhili Xu,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Division of Cellular and Gene Therapies, FDA Center for Biologics Evaluation and Research, Silver Spring, Maryland, United States of America

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• Rituparna Moitra,

  Roles Investigation, Writing – review & editing

  Affiliation Division of Cellular and Gene Therapies, FDA Center for Biologics Evaluation and Research, Silver Spring, Maryland, United States of America

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• Donna J. Palmer,

  Roles Resources

  Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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• Philip Ng,

  Roles Resources, Writing – review & editing

  Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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• Andrew P. Byrnes

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Andrew.Byrnes@fda.hhs.gov

  Affiliation Division of Cellular and Gene Therapies, FDA Center for Biologics Evaluation and Research, Silver Spring, Maryland, United States of America

  https://orcid.org/0000-0003-1135-2629

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