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Open Access
Peer-reviewed
Research Article
MERS-CoV ORF4b is a virulence factor involved in the inflammatory pathology induced in the lungs of mice
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Melissa Bello-Perez ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing
* E-mail: isola@cnb.csic.es (I.S); mloreto@cnb.csic.es (M.B.P)
¶‡ MB-P and JH-T contributed equally to this article. Author order was determined both alphabetically and in order of increasing seniority.
Affiliation Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin, Madrid, Spain
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Jesús Hurtado-Tamayo ,
Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing
¶‡ MB-P and JH-T contributed equally to this article. Author order was determined both alphabetically and in order of increasing seniority.
Affiliation Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin, Madrid, Spain
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Ricardo Requena-Platek,
Roles Investigation, Methodology, Validation
Affiliation Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin, Madrid, Spain
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Javier Canton,
Roles Investigation, Methodology, Validation
Current address: International Institute for Defense and Security (CISDE), Seville, Spain.
Affiliation Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin, Madrid, Spain
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Pedro José Sánchez-Cordón,
Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing
Affiliation Veterinary Pathology Department, Animal Health Research Center (CISA), National Institute of Research, Agricultural and Food Technology (INIA-CSIC), Valdeolmos, Madrid, Spain
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Raúl Fernandez-Delgado,
Roles Investigation, Methodology, Validation
Current address: Department. Infectious Diseases And One Health. Animal Health Research Center (CISA). National Institute of Research, Agricultural and Food Technology (INIA-CSIC), Madrid, Spain.
Affiliation Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin, Madrid, Spain
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Luis Enjuanes,
Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing
Affiliation Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin, Madrid, Spain
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Isabel Sola
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing
* E-mail: isola@cnb.csic.es (I.S); mloreto@cnb.csic.es (M.B.P)
Affiliation Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin, Madrid, Spain
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MERS-CoV ORF4b is a virulence factor involved in the inflammatory pathology induced in the lungs of mice
- Melissa Bello-Perez,
- Jesús Hurtado-Tamayo,
- Ricardo Requena-Platek,
- Javier Canton,
- Pedro José Sánchez-Cordón,
- Raúl Fernandez-Delgado,
- Luis Enjuanes,
- Isabel Sola
- Published: September 21, 2022
- https://doi.org/10.1371/journal.ppat.1010834