Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus

• Cameron Adams,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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• Derek L. Carbaugh ,

  Contributed equally to this work with: Derek L. Carbaugh, Bo Shu

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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• Bo Shu ,

  Contributed equally to this work with: Derek L. Carbaugh, Bo Shu

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore, Centre for Bio-Imaging Sciences, Department of Biological Sciences, National University of Singapore, Singapore, Singapore

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• Thiam-Seng Ng,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliations Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore, Centre for Bio-Imaging Sciences, Department of Biological Sciences, National University of Singapore, Singapore, Singapore

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• Izabella N. Castillo,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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• Ryan Bhowmik,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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• Bruno Segovia-Chumbez,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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• Ana C. Puhl,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Center for Integrative Chemical Biology and Drug Discovery, Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Stephen Graham,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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• Sean A. Diehl,

  Roles Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, United States of America

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• Helen M. Lazear,

  Roles Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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• Shee-mei Lok,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing

  Affiliations Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore, Centre for Bio-Imaging Sciences, Department of Biological Sciences, National University of Singapore, Singapore, Singapore

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• Aravinda M. de Silva ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: aravinda_desilva@med.unc.edu (AMS); prem@med.unc.edu (LP)

  Affiliation Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0003-3317-5950

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• Lakshmanane Premkumar

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: aravinda_desilva@med.unc.edu (AMS); prem@med.unc.edu (LP)

  Affiliation Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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