Echovirus 11 infection induces pyroptotic cell death by facilitating NLRP3 inflammasome activation

Chong Wang; Ruyi Yang; Fengxia Yang; Yang Han; Yujie Ren; Xiaobei Xiong; Xingyun Wang; Yidan Bi; Lijun Li; Yang Qiu; Yi Xu; Xi Zhou

doi:10.1371/journal.ppat.1010787

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Open Access

Peer-reviewed

Research Article

Echovirus 11 infection induces pyroptotic cell death by facilitating NLRP3 inflammasome activation

Chong Wang ,

Contributed equally to this work with: Chong Wang, Ruyi Yang

Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliations Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou, Guangdong, China, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China
⨯
Ruyi Yang ,

Contributed equally to this work with: Chong Wang, Ruyi Yang

Roles Investigation

Affiliation State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China
⨯
Fengxia Yang,

Roles Investigation

Affiliation Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou, Guangdong, China
⨯
Yang Han,

Roles Investigation

Affiliation Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, Wuhan Jinyintan Hospital, Wuhan, Hubei, China
⨯
Yujie Ren,

Roles Investigation

Affiliation State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China
⨯
Xiaobei Xiong,

Roles Investigation

Affiliation State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China
⨯
Xingyun Wang,

Roles Investigation

Affiliation Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou, Guangdong, China
⨯
Yidan Bi,

Roles Investigation

Affiliation Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou, Guangdong, China
⨯
Lijun Li,

Roles Investigation

Affiliation Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou, Guangdong, China
⨯
Yang Qiu ,

Roles Formal analysis, Writing – original draft, Writing – review & editing

* E-mail: yangqiu@wh.iov.cn (YQ); xuyi70@163.com (YX); zhouxi@wh.iov.cn (XZ)

Affiliation State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China
⨯
Yi Xu ,

Roles Conceptualization, Formal analysis, Supervision

* E-mail: yangqiu@wh.iov.cn (YQ); xuyi70@163.com (YX); zhouxi@wh.iov.cn (XZ)

Affiliation Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou, Guangdong, China
⨯
Xi Zhou

Roles Conceptualization, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

* E-mail: yangqiu@wh.iov.cn (YQ); xuyi70@163.com (YX); zhouxi@wh.iov.cn (XZ)

Affiliation State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China

https://orcid.org/0000-0002-3846-5079

⨯

Echovirus 11 infection induces pyroptotic cell death by facilitating NLRP3 inflammasome activation

Chong Wang,
Ruyi Yang,
Fengxia Yang,
Yang Han,
Yujie Ren,
Xiaobei Xiong,
Xingyun Wang,
Yidan Bi,
Lijun Li,
Yang Qiu

Published: August 26, 2022
https://doi.org/10.1371/journal.ppat.1010787

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