After the virus has cleared—Can preclinical models be employed for Long COVID research?

Ethan B. Jansen; Spencer N. Orvold; Cynthia L. Swan; Anthony Yourkowski; Brittany M. Thivierge; Magen E. Francis; Anni Ge; Melissa Rioux; Joseph Darbellay; John G. Howland; Alyson A. Kelvin

doi:10.1371/journal.ppat.1010741

Loading metrics

Open Access

Review articles synthesize the best available evidence on a topic relevant to the pathogens community.

See all article types »

After the virus has cleared—Can preclinical models be employed for Long COVID research?

Ethan B. Jansen,

Affiliations Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

https://orcid.org/0000-0002-7212-7487

⨯
Spencer N. Orvold,

Affiliation Department of Anatomy, Physiology, and Pharmacology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
⨯
Cynthia L. Swan,

Affiliation Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
⨯
Anthony Yourkowski,

Affiliations Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
⨯
Brittany M. Thivierge,

Affiliation Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
⨯
Magen E. Francis,

Affiliations Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
⨯
Anni Ge,

Affiliation Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
⨯
Melissa Rioux,

Affiliation Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
⨯
Joseph Darbellay,

Affiliation Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
⨯
John G. Howland,

Affiliation Department of Anatomy, Physiology, and Pharmacology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
⨯
Alyson A. Kelvin

* E-mail: alyson.kelvin@usask.ca

Affiliation Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

https://orcid.org/0000-0003-0940-0847

⨯

After the virus has cleared—Can preclinical models be employed for Long COVID research?

Ethan B. Jansen,
Spencer N. Orvold,
Cynthia L. Swan,
Anthony Yourkowski,
Brittany M. Thivierge,
Magen E. Francis,
Anni Ge,
Melissa Rioux,
Joseph Darbellay,
John G. Howland

Published: September 7, 2022
https://doi.org/10.1371/journal.ppat.1010741

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

SARS CoV 2
Is the Subject Area "SARS CoV 2" applicable to this article?

Thanks for your feedback.
COVID 19
Is the Subject Area "COVID 19" applicable to this article?

Thanks for your feedback.
Hamsters
Is the Subject Area "Hamsters" applicable to this article?

Thanks for your feedback.
Macaque
Is the Subject Area "Macaque" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Ferrets
Is the Subject Area "Ferrets" applicable to this article?

Thanks for your feedback.
Respiratory infections
Is the Subject Area "Respiratory infections" applicable to this article?

Thanks for your feedback.
Respiratory physiology
Is the Subject Area "Respiratory physiology" applicable to this article?

Thanks for your feedback.