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Potent universal beta-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody
- Michael S. Piepenbrink ,
- Jun-Gyu Park ,
- Ashlesha Deshpande,
- Andreas Loos,
- Chengjin Ye,
- Madhubanti Basu,
- Sanghita Sarkar,
- Ahmed Magdy Khalil,
- David Chauvin,
- Jennifer Woo,
- Philip Lovalenti,
- Nathaniel B. Erdmann,
- Paul A. Goepfert,
- Vu L. Truong,
- Richard A. Bowen,
- Mark R. Walter ,
- Luis Martinez-Sobrido ,
- [ ... ],
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James J. Kobie
Roles Conceptualization, Investigation, Supervision, Writing – original draft, Writing – review & editing
* E-mail: walter@uab.edu (MRW); lmartinez@txbiomed.org (LM-S); jjkobie@uabmc.edu (JJK)
Affiliation Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
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https://orcid.org/0000-0001-8069-0272
Potent universal beta-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody
- Michael S. Piepenbrink,
- Jun-Gyu Park,
- Ashlesha Deshpande,
- Andreas Loos,
- Chengjin Ye,
- Madhubanti Basu,
- Sanghita Sarkar,
- Ahmed Magdy Khalil,
- David Chauvin,
- Jennifer Woo
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- Published: July 21, 2022
- https://doi.org/10.1371/journal.ppat.1010691