Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry

• Lalita Priyamvada ,

  Contributed equally to this work with: Lalita Priyamvada, Wouter W. Kallemeijn

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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• Wouter W. Kallemeijn ,

  Contributed equally to this work with: Lalita Priyamvada, Wouter W. Kallemeijn

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London, United Kingdom, The Francis Crick Institute, London, United Kingdom

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• Monica Faronato,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft

  Affiliations Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London, United Kingdom, The Francis Crick Institute, London, United Kingdom

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• Kimberly Wilkins,

  Roles Data curation, Investigation

  Affiliation Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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• Cynthia S. Goldsmith,

  Roles Data curation, Investigation

  Affiliation Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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• Catherine A. Cotter,

  Roles Data curation, Formal analysis

  Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Suany Ojeda,

  Roles Data curation, Formal analysis

  Affiliations Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, Clinipace, Morrisville, North Carolina, United States of America

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• Roberto Solari,

  Roles Conceptualization, Resources, Writing – original draft

  Affiliation National Heart and Lung Institute, Imperial College of Science, Technology & Medicine, London, United Kingdom

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• Bernard Moss,

  Roles Formal analysis, Investigation, Resources, Writing – review & editing

  Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Edward W. Tate ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: e.tate@imperial.ac.uk (EWT); spanayampalli@cdc.gov (PSS)

  Affiliations Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London, United Kingdom, The Francis Crick Institute, London, United Kingdom

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• Panayampalli Subbian Satheshkumar

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: e.tate@imperial.ac.uk (EWT); spanayampalli@cdc.gov (PSS)

  Affiliation Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0003-1472-1418

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