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Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target
- Yongchang Xu ,
- Jie Yang ,
- Weihui Li ,
- Shuaijie Song ,
- Yu Shi ,
- Lihan Wu,
- Jingdu Sun,
- Mengyun Hou,
- Jinzi Wang,
- Xu Jia,
- Huimin Zhang,
- Man Huang,
- Ting Lu,
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Jianhua Gan ,
Roles Conceptualization, Formal analysis, Methodology, Resources, Software, Visualization, Writing – original draft
* E-mail: ganjhh@fudan.edu.cn (JG); fengyj@zju.edu.cn (YF)
Affiliation Shanghai Public Health Clinical Center, State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Biochemistry and Biophysics, School of Life Science, Fudan University, Shanghai, The People’s Republic of China
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Youjun Feng
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: ganjhh@fudan.edu.cn (JG); fengyj@zju.edu.cn (YF)
Affiliations Departments of Microbiology, and General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, The People’s Republic of China, College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang, The People’s Republic of China, Non-coding RNA and Drug Discovery Key Laboratory of Sichuan Province, Chengdu Medical College, Chengdu, Sichuan, The People’s Republic of China
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https://orcid.org/0000-0002-8438-8852
Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target
- Yongchang Xu,
- Jie Yang,
- Weihui Li,
- Shuaijie Song,
- Yu Shi,
- Lihan Wu,
- Jingdu Sun,
- Mengyun Hou,
- Jinzi Wang,
- Xu Jia
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- Published: July 11, 2022
- https://doi.org/10.1371/journal.ppat.1010615