SAFA facilitates chromatin opening of immune genes through interacting with anti-viral host RNAs

• Lili Cao ,

  Contributed equally to this work with: Lili Cao, Yujie Luo

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft

  Affiliations Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China, Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China

  https://orcid.org/0000-0003-4608-0723

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• Yujie Luo ,

  Contributed equally to this work with: Lili Cao, Yujie Luo

  Roles Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing

  Affiliation Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China

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• Xuefei Guo,

  Roles Data curation, Software, Validation, Visualization

  Affiliation Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China

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• Shengde Liu,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, Beijing, China

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• Siji Li,

  Roles Methodology, Software, Writing – review & editing

  Affiliation Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China

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• Junhong Li,

  Roles Validation, Writing – review & editing

  Affiliation CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China

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• Zeming Zhang,

  Roles Methodology, Visualization

  Affiliation Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China

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• Yingchi Zhao,

  Roles Data curation, Methodology

  Affiliation Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China

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• Qiao Zhang,

  Roles Methodology, Supervision

  Affiliation School of Medicine, Jinan University, Guangzhou, Guangdong, China

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• Feng Gao,

  Roles Supervision, Validation

  Affiliation School of Medicine, Jinan University, Guangzhou, Guangdong, China

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• Xiong Ji,

  Roles Methodology, Software, Supervision

  Affiliation Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China

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• Xiang Gao,

  Roles Supervision, Writing – review & editing

  Affiliation State Key Laboratory of Microbial Technology, Microbial Technology Institute, School of life science, Shandong University, Qingdao, China

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• Yunfei Li ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Resources, Writing – review & editing

  * E-mail: 1711110048@bjmu.edu.cn (YL); fupingyou@hsc.pku.edu.cn (FY)

  Affiliation Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China

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• Fuping You

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: 1711110048@bjmu.edu.cn (YL); fupingyou@hsc.pku.edu.cn (FY)

  Affiliation Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China

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