Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes

Nela Klimova; Jana Holubova; Gaia Streparola; Jakub Tomala; Ludmila Brazdilova; Ondrej Stanek; Ladislav Bumba; Peter Sebo

doi:10.1371/journal.ppat.1010577

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Open Access

Peer-reviewed

Research Article

Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes

Nela Klimova,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Institute of Microbiology of the Czech Academy of Sciences,Prague, Czech Republic, Faculty of Sciences, Charles University, Prague, Czech Republic
⨯
Jana Holubova,

Roles Investigation, Methodology, Validation

Affiliation Institute of Microbiology of the Czech Academy of Sciences,Prague, Czech Republic
⨯
Gaia Streparola,

Roles Investigation, Methodology

Affiliations Institute of Microbiology of the Czech Academy of Sciences,Prague, Czech Republic, Czech Centre for Phenogenomics BIOCEV, Vestec, Czech Republic
⨯
Jakub Tomala,

Roles Investigation, Methodology

Affiliations Institute of Microbiology of the Czech Academy of Sciences,Prague, Czech Republic, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic
⨯
Ludmila Brazdilova,

Roles Formal analysis, Investigation, Methodology

Affiliations Institute of Microbiology of the Czech Academy of Sciences,Prague, Czech Republic, Faculty of Sciences, Charles University, Prague, Czech Republic
⨯
Ondrej Stanek,

Roles Investigation, Methodology

Affiliation Institute of Microbiology of the Czech Academy of Sciences,Prague, Czech Republic
⨯
Ladislav Bumba ,

Roles Conceptualization, Formal analysis, Validation, Visualization, Writing – review & editing

* E-mail: bumba@biomed.cas.cz (LB); sebo@biomed.cas.cz (PS)

Affiliation Institute of Microbiology of the Czech Academy of Sciences,Prague, Czech Republic
⨯
Peter Sebo

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: bumba@biomed.cas.cz (LB); sebo@biomed.cas.cz (PS)

Affiliation Institute of Microbiology of the Czech Academy of Sciences,Prague, Czech Republic

https://orcid.org/0000-0002-9755-7715

⨯

Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes

Nela Klimova,
Jana Holubova,
Gaia Streparola,
Jakub Tomala,
Ludmila Brazdilova,
Ondrej Stanek,
Ladislav Bumba,
Peter Sebo

Published: June 6, 2022
https://doi.org/10.1371/journal.ppat.1010577

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Bordetella pertussis
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Pertussis
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Lymph nodes
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Toxins
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