T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin

Birgitta Lindqvist; Bianca B. Jütte; Luca Love; Wlaa Assi; Julie Roux; Anders Sönnerborg; Tugsan Tezil; Eric Verdin; J. Peter Svensson

doi:10.1371/journal.ppat.1010555

Loading metrics

Open Access

Peer-reviewed

Research Article

T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin

Birgitta Lindqvist ,

Contributed equally to this work with: Birgitta Lindqvist, Bianca B. Jütte, Luca Love

Roles Investigation

Affiliation Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
⨯
Bianca B. Jütte ,

Contributed equally to this work with: Birgitta Lindqvist, Bianca B. Jütte, Luca Love

Roles Investigation, Writing – review & editing

Affiliation Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
⨯
Luca Love ,

Contributed equally to this work with: Birgitta Lindqvist, Bianca B. Jütte, Luca Love

Roles Investigation, Writing – review & editing

Affiliation Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
⨯
Wlaa Assi,

Roles Investigation, Writing – review & editing

Affiliations Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden, Laboratory of Viral Infectious Diseases, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan
⨯
Julie Roux,

Roles Writing – review & editing

Affiliation Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
⨯
Anders Sönnerborg,

Roles Funding acquisition, Writing – review & editing

Affiliation Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden, Division of Infectious Diseases, Department of Medicine Huddinge, I73, Karolinska University Hospital, Stockholm, Sweden
⨯
Tugsan Tezil,

Roles Investigation

Affiliation Buck Institute for Research on Aging, Novato, California, United States of America
⨯
Eric Verdin,

Roles Resources

Affiliation Buck Institute for Research on Aging, Novato, California, United States of America
⨯
J. Peter Svensson

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Software, Supervision, Writing – original draft

* E-mail: peter.svensson@ki.se

Affiliation Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

https://orcid.org/0000-0002-5863-6250

⨯

T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin

Birgitta Lindqvist,
Bianca B. Jütte,
Luca Love,
Wlaa Assi,
Julie Roux,
Anders Sönnerborg,
Tugsan Tezil,
Eric Verdin,
J. Peter Svensson

Published: June 6, 2022
https://doi.org/10.1371/journal.ppat.1010555

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

HIV-1
Is the Subject Area "HIV-1" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Chromatin
Is the Subject Area "Chromatin" applicable to this article?

Thanks for your feedback.
Viral persistence and latency
Is the Subject Area "Viral persistence and latency" applicable to this article?

Thanks for your feedback.
Cell cycle and cell division
Is the Subject Area "Cell cycle and cell division" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.