Encapsulation of the septal cell wall protects Streptococcus pneumoniae from its major peptidoglycan hydrolase and host defenses

• Joana Figueiredo ,

  Contributed equally to this work with: Joana Figueiredo, Mafalda Xavier Henriques

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

  Affiliations Laboratory of Bacterial Cell Surfaces and Pathogenesis, UCIBIO-Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade Nova de Lisboa, Monte da Caparica, Portugal, Laboratory of Bacterial Cell Surfaces and Pathogenesis, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal, Associate Laboratory i4HB—Institute for Health and Bioeconomy, School of Science and Technology, NOVA University Lisbon, Monte da Caparica, Portugal

  https://orcid.org/0000-0002-6804-0522

  ⨯
• Mafalda Xavier Henriques ,

  Contributed equally to this work with: Joana Figueiredo, Mafalda Xavier Henriques

  Roles Conceptualization, Data curation, Formal analysis, Investigation

  Affiliation Laboratory of Bacterial Cell Surfaces and Pathogenesis, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

  ⨯
• Maria João Catalão,

  Roles Investigation, Methodology

  Affiliations Laboratory of Bacterial Cell Surfaces and Pathogenesis, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal, Host-Pathogen Interaction Unit, Faculty of Pharmacy, Research Institute for Medicines, iMed-ULisboa, Universidade de Lisboa, Lisboa, Portugal

  ⨯
• Sara Pinheiro,

  Roles Investigation

  Affiliations Laboratory of Bacterial Cell Surfaces and Pathogenesis, UCIBIO-Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade Nova de Lisboa, Monte da Caparica, Portugal, Associate Laboratory i4HB—Institute for Health and Bioeconomy, School of Science and Technology, NOVA University Lisbon, Monte da Caparica, Portugal

  ⨯
• Ana Rita Narciso,

  Roles Investigation

  Affiliation Laboratory of Bacterial Cell Surfaces and Pathogenesis, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

  https://orcid.org/0000-0003-1316-3856

  ⨯
• Francisco Mesquita,

  Roles Investigation

  Affiliation Group of Molecular Microbiology, Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal

  https://orcid.org/0000-0002-3777-825X

  ⨯
• Bruno Manuel Saraiva,

  Roles Software

  Affiliation Laboratory of Bacterial Cell Biology, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal

  https://orcid.org/0000-0002-9151-5477

  ⨯
• Madalena Carido,

  Roles Investigation, Methodology

  Affiliation Laboratory of Bacterial Cell Surfaces and Pathogenesis, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

  ⨯
• Didier Cabanes,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Group of Molecular Microbiology, Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal

  ⨯
• Mariana Gomes Pinho,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Laboratory of Bacterial Cell Biology, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal

  ⨯
• Sérgio Raposo Filipe

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: sfilipe@fct.unl.pt

  Affiliations Laboratory of Bacterial Cell Surfaces and Pathogenesis, UCIBIO-Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade Nova de Lisboa, Monte da Caparica, Portugal, Laboratory of Bacterial Cell Surfaces and Pathogenesis, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal, Associate Laboratory i4HB—Institute for Health and Bioeconomy, School of Science and Technology, NOVA University Lisbon, Monte da Caparica, Portugal

  https://orcid.org/0000-0002-4485-832X

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