The SUMO E3 ligase activity of ORF45 determines KSHV lytic replication

• Zhenshan Liu ,

  Contributed equally to this work with: Zhenshan Liu, Xin Wang, Chengrong Liu, Hongying Deng, Wenshu Li

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Validation, Visualization

  Affiliations Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Xin Wang ,

  Contributed equally to this work with: Zhenshan Liu, Xin Wang, Chengrong Liu, Hongying Deng, Wenshu Li

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation

  Affiliations Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Chengrong Liu ,

  Contributed equally to this work with: Zhenshan Liu, Xin Wang, Chengrong Liu, Hongying Deng, Wenshu Li

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation

  Affiliations Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Hongying Deng ,

  Contributed equally to this work with: Zhenshan Liu, Xin Wang, Chengrong Liu, Hongying Deng, Wenshu Li

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation Department of Biological Science, Florida State University, Tallahassee, Florida, United States of America

  ⨯
• Wenshu Li ,

  Contributed equally to this work with: Zhenshan Liu, Xin Wang, Chengrong Liu, Hongying Deng, Wenshu Li

  Roles Investigation

  Affiliation College of Arts and Sciences, New York University Shanghai, Shanghai, China

  ⨯
• Xiaoqian Wang,

  Roles Investigation

  Affiliations Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Joint Ph.D. Degree Program between SJTU-SM and HUJI-MED, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Xue Xu,

  Roles Investigation

  Affiliations Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Maggie Z. X. Xiao,

  Roles Investigation, Visualization, Writing – original draft

  Affiliation Faculty of Medicine, University of Alberta, Edmonton, Alberta, Canada

  ⨯
• Chunxia Wang,

  Roles Investigation

  Affiliations Department of Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, China, Institute of Pediatric Infection, Immunity and Intensive Care Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Yucai Zhang,

  Roles Investigation

  Affiliations Department of Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, China, Institute of Pediatric Infection, Immunity and Intensive Care Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Joyce Fu,

  Roles Investigation, Software, Visualization

  Affiliation Department of Statistics, University of California, Riverside, Riverside, California, United States of America

  ⨯
• Fanxiu Zhu ,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: fzhu@bio.fsu.edu (FZ); liangqiming@shsmu.edu.cn (QL)

  Affiliation Department of Biological Science, Florida State University, Tallahassee, Florida, United States of America

  ⨯
• Qiming Liang

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: fzhu@bio.fsu.edu (FZ); liangqiming@shsmu.edu.cn (QL)

  Affiliations Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Joint Ph.D. Degree Program between SJTU-SM and HUJI-MED, Shanghai Jiao Tong University, Shanghai, China, Institute of Pediatric Infection, Immunity and Intensive Care Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China, State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China, Research Center of Translational Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, China

  https://orcid.org/0000-0003-4792-1547

  ⨯