Regulation of EBNA1 protein stability and DNA replication activity by PLOD1 lysine hydroxylase

Jayaraju Dheekollu; Andreas Wiedmer; Samantha S. Soldan; Leonardo Josué Castro- Muñoz; Christopher Chen; Hsin-Yao Tang; David W. Speicher; Paul M. Lieberman

doi:10.1371/journal.ppat.1010478

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Peer-reviewed

Research Article

Regulation of EBNA1 protein stability and DNA replication activity by PLOD1 lysine hydroxylase

Jayaraju Dheekollu,

Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America
⨯
Andreas Wiedmer,

Roles Investigation

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America
⨯
Samantha S. Soldan,

Roles Investigation, Methodology, Visualization, Writing – original draft

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America
⨯
Leonardo Josué Castro- Muñoz,

Roles Investigation, Methodology, Visualization

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America
⨯
Christopher Chen,

Roles Investigation, Visualization, Writing – original draft

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America
⨯
Hsin-Yao Tang,

Roles Investigation, Methodology, Visualization, Writing – original draft

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America
⨯
David W. Speicher,

Roles Conceptualization, Methodology, Resources, Supervision

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America
⨯
Paul M. Lieberman

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: lieberman@wistar.org

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America

https://orcid.org/0000-0002-3935-9921

⨯

Regulation of EBNA1 protein stability and DNA replication activity by PLOD1 lysine hydroxylase

Jayaraju Dheekollu,
Andreas Wiedmer,
Samantha S. Soldan,
Leonardo Josué Castro- Muñoz,
Christopher Chen,
Hsin-Yao Tang,
David W. Speicher,
Paul M. Lieberman

Published: June 1, 2023
https://doi.org/10.1371/journal.ppat.1010478

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DNA replication
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Lysine
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Hydroxylation
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Transfection
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Small interfering RNA
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Actins
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DNA-binding proteins
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Immunoprecipitation
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